Correlations of the renin‐angiotensin‐system (RAS) gene polymorphisms with cardiac growth factors endothelin‐1 and angiotensin II in high performance athletes
Abstract:Background: The regulation of myocardial mass in athletes involves complex interactions between physical stress, cardiac growth factors (GF), and the individual genetic background. Studies suggest the renin-angiotensin-system (RAS) plays a key role in the development of myocardial hypertrophy. Genetic polymorphisms of the RAS, associated with an activation, have been shown to correlate with left ventricular mass (LVM) in athletes. It is not clear whether these polymorphisms influence angiotensin (A) II levels … Show more
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