Correlations between the value of the dermatological quality of life index and clinical and anamnestic indicators in ukrainian men and women with urticaria

Abstract

Annotation. The increasing prevalence of urticaria and its significant impact on the quality of life of patients is a real challenge and a difficult task to solve both for family doctors and for dermatovenerologists. The study of correlations between the dermatological quality of life index (DLQI) and clinical and anamnestic indicators allows a deeper understanding of how this disease affects various aspects of the patients' lives, in particular, taking into account the gender and age characteristics of Ukrainian patients. The obtained results may contribute to the development of more effective and personalized approaches to the treatment and support of patients with urticaria, which in turn will improve their general well-being and quality of life. The aim of the work is to establish the peculiarities of the relationship between the value of the dermatological quality of life index and clinical and anamnestic indicators in young Ukrainian men and women with acute or chronic urticaria of a mild and severe course. Ukrainian men (n=40) and women (n=40) of young age (25-44 years according to the age periodization of WHO, 2015), patients with acute and chronic urticaria of mild and severe course, underwent a clinical, anamnestic and dermatological examination. The degree of negative impact of urticaria on various aspects of patients' lives was determined using the dermatological quality of life index. All patients also underwent a questionnaire to determine the nature of work and various negative factors affecting the skin. The assessment of correlations between the value of the dermatological quality of life index and clinical and anamnestic indicators was carried out using non-parametric statistics of Spearman in the license package "Statistica 6.0". As a result of the conducted studies, multiple direct and inverse correlations, mainly of medium strength and unreliable, were established between the dermatoscopic quality of life index and clinical and anamnestic indicators (in men r= from 0.31 to 0.82 and r= from -0.31 to -0.73; in women r= from 0.30 to 0.71 and r= from -0.31 to -0.75), which have pronounced manifestations of sexual dimorphism both in the number and strength, and often in the direction of the obtained connections.