Correlation Oflipid Profile With Glycated Hemoglobin (Hba1c) in Diabetic Patients in King Abdullah Hospital, Bisha, Saudi Arabia

Abstract

Background: This study aimed to observe the lipid profile in diabeticpatients and to find out correlation between glycated hemoglobin (HbA 1C ) and lipid profile. Methods: Lipid profiles, fasting blood sugar and HbA 1C values of 100 diabetic patients were studied. Blood samples of 41 male and 59 female diabetic patients were assessed for fasting blood glucose (FBG), total cholesterol, TG, LDL and HDL andHbA 1C . Results: The 100 diabetic patients were havingHbA 1C mean valuewas 9.1±1.9%. Means of HbA 1C , cholesterol, HDL, LDL, and FBG were higher in females than males. In contrast, means of triglycerides and age were lower in female than males. All parameters have positive correlation with HbA 1C . Significant correlation of HbA 1C levels wereseen with FBG (p<0.01).TGwas having negative correlation with HDL, LDL and FBG. The HDL values of diabetic patients were negatively significantly correlated with age with p value 0.008. LDL levels were significantly correlated with cholesteroland age (p<0.01 and 0.049).About 60% of diabetic patientstheir HDL was >46mg/dl (1.2mmol/L) and >70% were having HDL>30mg/dl (0.8mmol/L). Findings indicate>50% of patients participated in this study may be at low risk, or in a good diabetic control or on medication, since, poor glycemic control in diabetic patients can lead to decreased HDL. Conclusion: Results in this study indicated the need for therapeutic attention for diabetic patients, especially those who are of small ages.Depending on antidiabetic medications only is not enough to treat diabetic patients.