Correlation of Thyroid Imaging Reporting and Data System [TI-RADS] and fine needle aspiration: experience in 1,000 nodules

Rahal, Antônio; Falsarella, Priscila Mina; Rocha, Rafael Dahmer; Lima, João Paulo Bacellar Costa; Iani, M.J.; Vieira, F. M.; Queiroz, Marcos Roberto Gomes de; Hidal, Jairo Tabacow; Neto, Miguel José Francisco; Garcia, Rodrigo Gobbo; Funari, Marcelo Buarque de Gusmão

doi:10.1590/s1679-45082016ao3640

Cited by 27 publications

(20 citation statements)

References 17 publications

(26 reference statements)

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“…Um achado inesperado em nosso estudo foi a parcela de nódulos Bethesda I (citopatologia insatisfatória), representando 24,4% dos nódulos puncionados, sendo superior ao encontrado na literatura (20)(21)(22) . Em contrapartida, as características epidemiológicas foram semelhantes ao encontrado em outros artigos, com uma média de idade de 53,2 anos ± 13,4 anos (9,(22)(23)(24)(25) , tamanho médio do nódulo de 2,1 cm (23,26) e predomínio do sexo feminino (9,(22)(23)(24) .…”

Section: Discussionunclassified

Correlação Entre Critérios Ultrassonográfico Acr Ti-Rads E Citopatológico Bethesda Na Avaliação De Nódulos Tireoidianos

Rocha

Silva

Soares

2018

Rev. Hosp. Univ. UFPI

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INTRODUCTION: Thyroid nodules are quite common in the population, however, distinguishing malignant thyroid nodules from benign ones constitutes a challenge. Ultrasonography (US) is a fundamental tool in the diagnosis of thyroid cancer. In 2017, the American College of Radiology released its recommendations for US analysis of thyroid, establishing the ACR TI-RADS, in an attempt to standardize indications for fine needle aspiration (FNA) between endocrinologists and radiologists. The Bethesda score obtained by FNA at one time provides subsidy for further surgery. The indication of FNA and the categorization of the nodule based on ultrasonographic characteristics, however, remains controversial. OBJECTIVES: To determine the correlation between thyroid US and FNA findings using ACR TI-RADS and Bethesda criteria in patients followed at HU-UFPI from January to June 2017. METHOD: Cross-sectional and observational study. The variables considered were sex, age, nodule size, ACR TI-RADS and Bethesda. For data analysis, means and percentages were obtained, and Chi-square, Student's t and Kappa tests were used. RESULTS: A total of 151 patients were evaluated, of which 94.7% were female. The mean nodule size was 2.1 cm and the mean age was 53.2 years. Among the variables, the size of the nodule was the most associated with the Bethesda classification. There was a positive association between the ACR TI-RADS and Bethesda methods. CONCLUSION: There was a correlation between the ACR TI-RADS ultrasonographic method and the Bethesda cytopathologic method. However, more studies are needed to determine the reliability of the ultrasonographic method.

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Section: Discussionunclassified

Correlação Entre Critérios Ultrassonográfico Acr Ti-Rads E Citopatológico Bethesda Na Avaliação De Nódulos Tireoidianos

Rocha

Silva

Soares

2018

Rev. Hosp. Univ. UFPI

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“…The included studies consisted mainly of prospective (n=4) and retrospective studies (n=4) followed by reviews/guidelines (n=3) and a multi-center study (n=1). In terms of population characteristics, four larges studies consisted of 3,315 participants (3,822 nodules), 2921 participants (3,980 nodules), 1,241 participants (1,293 nodules), and 906 participants (1,000 nodules) [15,16,20,21]. Five comparatively small studies included 238 participants (272 nodules), 105 participants (nodules not reported), 100 participants (157 nodules), 100 participants (nodules not reported), and 84 participants (87 nodules) [17-19, 22,23].…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Five comparatively small studies included 238 participants (272 nodules), 105 participants (nodules not reported), 100 participants (157 nodules), 100 participants (nodules not reported), and 84 participants (87 nodules) [17-19, 22,23]. A total of 9,010 participants (10,611 nodules) were reported from all studies [14][15][16][17][18][19][20][21][22][23][24][25]. The proportion of participants who were male (nodules from male participants) reported from studies ranged from 14% to 33% (20-29%) [15][16][17][18][19]22,23].…”

Section: Study Characteristicsmentioning

confidence: 99%

“…In addition, the Bethesda classification system of histological reporting for FNAB of thyroid tissue was also reported. Eight (66%) studies reported the use of TIRADS [14][15][16][17][20][21][22][23] followed by two studies (8%) that used the ATA guidelines [18,20] and two (17%) studies that used the Bethesda system [19,24].…”

Section: Thyroid Nodule Classification Systemsmentioning

confidence: 99%

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Ultrasound Classification of Thyroid Nodules: A Systematic Review

Mistry¹,

Hillyar²,

Nibber³

et al. 2020

Cureus

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Ultrasound (US) based classification systems exist for the stratification of thyroid nodules based on the risk for malignancy. This systematic review aimed to assess the evidence for the performance of US-based thyroid nodule classification systems through correlation with fine needle aspiration biopsy (FNAB). PubMed and Scopus were searched using keywords that included 'ultrasound classification', 'thyroid nodules', 'fine needle aspiration', and 'malignancy'. Inclusion criteria were as follows: studies/reviews reporting on US imaging for the classification of thyroid nodules. Exclusion criteria were as follows: no comparison between US imaging findings and histology reports based on FNAB, no full English text available/accessible. The database searches identified 66 publications. After evaluation, 12 studies met the inclusion criteria. Two US-based classification systems for thyroid nodules were assessed: the Thyroid Imaging Reporting and Data System (TIRADS) and the American Thyroid Association (ATA) guidelines. For TIRADS, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) ranged from 70.6% to 97.4%, 29.3% to 90.4%, 23.3% to 64.3%, and 87.1% to 99.0%, respectively. The median sensitivity, specificity, PPV, and NPV for TIRADS was 90.0%, 57.4%, 49.0%, and 91.0%, respectively. One study comparing TIRADS with the ATA guidelines demonstrated that TIRADS was superior in terms of sensitivity, whereas the ATA guidelines were superior in terms of specificity and PPV. The high sensitivity and NPV of the US-based TIRADS classification system have excellent utility for correctly classifying nodules as positive for malignant disease and for predicting the absence of malignant disease. The paucity of studies assessing the ATA guidelines highlights avenues for further research comparing TIRADS with other systems of thyroid nodule classification.

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“…Similar to the already established Breast Imaging Reporting and Data System (BI‐RADS) for breast lesions, a Thyroid Imaging Reporting and Data System (TI‐RADS) was introduced to the field of thyroid ultrasound imaging in 2009 by Horvath, et al 3 Various formats of TI‐RADS have been applied in different studies performed outside of the United States. 4‐7 The American College of Radiology (ACR) published the white paper for its TI‐RADS in 2017. 8 The present study was initiated right before the publication of ACR's TI‐RADS.…”

Section: Introductionmentioning

confidence: 99%

A correlation study between thyroid imaging report and data systems and the Bethesda system for reporting thyroid cytology with surgical follow‐up‐ an ultrasound‐trained cytopathologist's experience

2020

Diagnostic Cytopathology

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Introduction Thyroid Imaging Reporting and Data Systems (TI‐RADS) including a modified system (M TI‐RADS) and American College Radiology (ACR) TI‐RADS are introduced. Correlation studies between both TI‐RADSs and The Bethesda System for Reporting Thyroid Cytology (TBSRTC) for Ultrasound‐guided fine‐needle aspiration (US‐FNA) cases with surgical follow‐up (SFU) are presented. Materials and Methods Three hundred and forty six thyroid US‐FNA cases performed at the US‐FNA clinic of Stony Brook University Hospital by an Ultrasound‐trained interventional Cytopathologist between December 1, 2014 to February 28, 2018 were reviewed. All ultrasound images from 346 cases were evaluated and assigned M TI‐RADS scores based on ultrasound features present in Table 1. One hundred and fifty four cases from Dcember 1, 2014 to February 28, 2016 were assigned scores using ACR TI‐RADS.TBSRTC category along with SFU data was collected and correlated with both TI‐RADS scores by using Pearson's correlation coefficient (r). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy for M TI‐RADS and TBSRTC were also calculated using SFU diagnosis as a gold standard. McNemar test was applied to evaluate the significance of the difference between M TI‐RADS and TBSRTC. Results Based on 346 thyroid nodules studied, the overall r‐value between M TI‐RADS scores and TBSRTC categories is 0.465. The r‐values between Composition, Echogenicity, Shape, Margin, Echogenic foci, the summary points, and the converted TR level of ACR TI‐RADS and TBSRTC are 0.145, 0.042, 0.259, 0.310, 0.405, and 0.379, respectively. Fifty (14.5%) cases have SFUs. Considering TI‐RADS 5&6 and TBSRTC 5&6 as positives, and TI‐RADS 2 and TBSRTC 2 as negatives, the Sensitivity, Specificity, PPV, NPV, and accuracy are 96%, 53%, 76%, 89%, 79% for TI‐RADS vs 100%, 93%, 96%, 100%, 97% for TBSRTC, respectively (P = .038). The data for indeterminate cases are summarized. Conclusion Both TI‐RADSs could be helpful to a moderate degree. M TI‐RADS appeared to correlate to TBSRTC slightly better than that of ACR TI‐RADS. TBSRTC is significantly more accurate than M TI‐RADS for the majority of determined cases.

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Correlation of Thyroid Imaging Reporting and Data System [TI-RADS] and fine needle aspiration: experience in 1,000 nodules

Cited by 27 publications

References 17 publications

Correlação Entre Critérios Ultrassonográfico Acr Ti-Rads E Citopatológico Bethesda Na Avaliação De Nódulos Tireoidianos

Correlação Entre Critérios Ultrassonográfico Acr Ti-Rads E Citopatológico Bethesda Na Avaliação De Nódulos Tireoidianos

Ultrasound Classification of Thyroid Nodules: A Systematic Review

A correlation study between thyroid imaging report and data systems and the Bethesda system for reporting thyroid cytology with surgical follow‐up‐ an ultrasound‐trained cytopathologist's experience

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