Correlation of the degree of conversion with the amount of elutable substances in nano-hybrid dental composites

Effect of the irradiance distribution from light curing units on the local micro-hardness of the surface of dental resins

“…This may lead to more inadequate curing due to irradiance spots over a restoration. Locally insufficient curing of the VLC RBCs is the consequence causing not only mechanical instability, but further problems such as the elution of residual monomers or other substances [42].…”

“…The primary problems of current RBCs are inadequate polymerization, shrinkage and corresponding shrinkage stress as well as elution of low molecular substances. This restricts the durability of restorations and may induce allergies or other health implications [26,42,43].…”

Genotoxic potential of dental bulk-fill resin composites

“…Furthermore, despite increased increment thickness of bulk-fill composites, monomer elution from these materials has been shown to be comparable to that of conventional composites, with the rate of elution being dependent on monomer molecular weight [51]. Beside the degree of conversion [8,52], the cross-link density of the polymer network affects the extent of monomer elution [53].…”

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites

“…These released components come into contact with oral tissues and may have various drawbacks like urticarial and mucosal reactions 5 , development of allergy and hypersensitivity reactions in patients 6 , modifications of gingival fibroblasts morphology and reduction on type I collagen protein 7 , immunosuppression or immunostimulation on mitogen-driven proliferation of purified T-lymphocytes and spleen cells 8 and DNA damage in primary human gingival fibroblasts, which underlines their genotoxic potential 9 . Many parameters can affect dental composite toxicity such as the shade of the composite, the light curing, the chemical composition of the resin monomer, the filler and the degree of conversion [10][11][12][13] . Since in vitro toxic potential of materials may predict in vivo situations and could be compared to clinical situations by the study of some relevant endpoints.…”