Correlation of the chemical composition of essential oils from Origanum vulgare subsp. virens with their in vitro activity against pathogenic yeasts and filamentous fungi

In vitro and in vivo antifungal activity of some essential oils against feline isolates of Microsporum canis

“…Furthermore both T. serpillum and O. vulgare contained p-cymene and g terpinene, which are biochemical precursors of thymol and carvacrol in the phenols biosynthetic pathway [17]. Differences have been reported among different samples of this plant, indicating the usefulness of promoting the crop culture of plants with high levels of antimycotic compounds such as carvacrol, g terpinene [18] and thymol [14].…”

Chemical Composition and Antifungal Properties of Essential Oil of <i>Origanum vulgare</i> Linnaeus (Lamiaceae) against <i>Sporothrix schenckii</i> and <i>Sporothrix brasiliensis</i>

“…The composition of O. vulgare essential oil from different geographical origins has been characterized by several authors, with carvacrol and thymol as the major components [6,15,16]. Other components have also been reported as important essential oil components, such as pcymene, γ-terpinene, caryophyllene, spathulenol and germacrene-D [12,13].…”

“…For antifungals, MFC is considered fungicidal when this value is equal to or less to four times the MIC value [20]. The concentration of carvacrol (15.7 %) also can to contribute for this fungicidal action, once previous reports have identified carvacrol and thymol as the main compounds associated with the antifungal activity of O. vulgare essential oil [6,16], though of thymol has not been detected. So, our results showed that the antifungal activity of O. vulgare essential oil can be associated with high concentration of γ-terpinene, besides carvacrol.…”

“…In this context, studies about evaluation of antifungal activities of essential oils have been carried [6] and a number of reports on new antifungal agents from plants have been reported [7].…”

Synthesis, Characterization and Antioxidant Activity of Carvacrol Based Sulfonates

“…However, the efficiency of these compounds in treatment is limited due to their poor water solubility and the requirement of high concentrations to reach a therapeutic effect [10,11]. Carvacrol, 5-isopropyl-3-methylphenol (Figure 1 (1)) is a major constituent of organo oil [12][13][14][15]. It is a phenolic monoterpenoid that exhibits several interesting biological activities [16][17][18].…”