Correlation of renal histopathology with sonographic findings

Moghazi, Sammy; Jones, Edria; Schroepple, Jill; Arya, Kraisith; McClellan, William; Hennigar, Randolph A.; O’Neill, W. Charles

doi:10.1111/j.1523-1755.2005.00230.x

Cited by 176 publications

(162 citation statements)

References 13 publications

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“…Sonography should be performed in all patients with CKD primarily to recognize advanced, irreversible kidney disease that would obviate any additional workup, including biopsy (11). Signs include small size, thin cortex, and cysts, but one must be cautious in making the diagnosis based solely on size in the 9-to 10-cm range when the kidneys are otherwise normal.…”

Section: Ckdmentioning

confidence: 99%

Renal Relevant Radiology

O’Neill

2014

Clinical Journal of the American Society of Nephrology

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Ultrasound is commonly used in nephrology for diagnostic studies of the kidneys and lower urinary tract and to guide percutaneous procedures, such as insertion of hemodialysis catheters and kidney biopsy. Nephrologists must, therefore, have a thorough understanding of renal anatomy and the sonographic appearance of normal kidneys and lower urinary tract, and they must be able to recognize common abnormalities. Proper interpretation requires correlation with the clinical scenario. With the advent of affordable, portable scanners, sonography has become a procedure that can be performed by nephrologists, and both training and certification in renal ultrasonography are available.

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Section: Ckdmentioning

confidence: 99%

Renal Relevant Radiology

O’Neill

2014

Clinical Journal of the American Society of Nephrology

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“…Intrinsic renal diseases (i.e. nephroangiosclerosis, hypertension, tubularinterstitial disease, diabetes mellitus, and severe bradycardia) can cause an increase of RI, even in the presence of normal serum creatinine levels [12]. In clinical practice the value of RI 0.7 is used to discriminate between normal and pathologic resistance to flow.…”

Section: Normal Findingsmentioning

confidence: 99%

“…In this location, signals are the strongest and most reproducible. Weak signals from peripheral (arcuate arteries) should be avoided [12,13]. Modern sonographic equipment has practically overcome problems due to obesity and bowel gas, so it is possible to study about 90% of the patients who are referred for investigation [14].…”

Section: Normal Findingsmentioning

confidence: 99%

Doppler ultrasound and renal artery stenosis: An overview

Granata

Fiorini²,

Andrulli

et al. 2009

Journal of Ultrasound

102

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KEYWORDSDoppler ultrasound; Ischemic nephropathy; Renal artery stenosis; Renovascular disease.Abstract Renovascular disease is a complex disorder, most commonly caused by fibromuscular dysplasia and atherosclerotic diseases. It can be found in one of three forms: asymptomatic renal artery stenosis (RAS), renovascular hypertension, and ischemic nephropathy. Particularly, the atherosclerotic form is a progressive disease that may lead to gradual and silent loss of renal function. Thus, early diagnosis of RAS is an important clinical objective since interventional therapy may improve or cure hypertension and preserve renal function. Screening for RAS is indicated in suspected renovascular hypertension or ischemic nephropathy, in order to identify patients in whom an endoluminal or surgical revascularization is advisable. Screening tests for RAS have improved considerably over the last decade. While captopril renography was widely used in the past, Doppler ultrasound (US) of the renal arteries (RAs), angio-CT, or magnetic resonance angiography (MRA) have replaced other modalities and they are now considered the screening tests of choice. An arteriogram is rarely needed for diagnostic purposes only. Color-Doppler US (CDUS) is a noninvasive, repeatable, relatively inexpensive diagnostic procedure which can accurately screen for renovascular diseases if performed by an expert. Moreover, the evaluation of the resistive index (RI) at Doppler US may be very useful in RAS affected patients for predicting the response to revascularization. However, when a discrepancy exists between clinical data and the results of Doppler US, additional tests are mandatory.Sommario La malattia nefrovascolare è un disordine complesso e le cause più comuni sono la malattia aterosclerotica e la displasia fibromuscolare. Classicamente si presenta in una delle seguenti tre forme: stenosi dell'arteria renale (SAR) asintomatica, associata a ipertensione nefrovascolare e/o con nefropatia ischemica. La SAR su base aterosclerotica è una malattia progressiva che può determinare in maniera asintomatica o paucisintomatica perdita graduale della funzione renale. Per tale motivo, la diagnosi precoce di SAR è un obiettivo clinico importante poiché la terapia interventistica può migliorare o curare l'ipertensione e preservare la funzione renale. Lo screening per SAR è indicato nel sospetto di ipertensione nefrovascolare o di nefropatia ischemica al fine di identificare i pazienti in cui è indicato un intervento di rivascolarizzazione. I test di screening per SAR sono migliorati considerevolmente durante l'ultimo decennio. Mentre la scintigrafia con test al captopril è stata utilizzata quasi esclusivamente nel passato, l'ecocolorDoppler delle arterie renali, l'angioTC e/o l'angioRM hanno sostituito le altre modalità di screening in molti centri. Per tale motivo l'arteriografia riveste sempre più un ruolo interventistico e solo di rado diagnostico. L'ecocolorDoppler è una procedura diagnostica non invasiva, ripetibile e relativamente economica che negli ultim...

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“…Consequently, these improvements simplified to evaluation of renal anatomic details as dimension, thickness and echogenicity of the renal cortex. These morphologic parameters are important, because ultrasonography shows findings of irreversible renal parenchymal disease as decrease in renal size, parenchymal atrophy, sclerosis and fibrosis [7]. In addition, it can help to assess prognosis and avoid unnecessary diagnostic or therapeutic procedures.…”

Section: Discussionmentioning

confidence: 99%

“…Renal length, cortical thickness and parenchymal echogenicity and collecting system dilatation are examined. In spite of these parameters correlate well with hystopathology, usually, these values may help in assesment disease chronicity rather than hystopathology [7]. Since 1980-1990 years, renal Doppler sonography has been used primarily for the screening of renovascular disease in native and transplant kidneys [8] .…”

Section: Introductionmentioning

confidence: 99%

Polycystic Ovary Syndrome: The Correlation Between Renal Doppler Ultrasound and Laboratory Parameters

Karadeli¹,

Üçkuyu²,

Çiftçi³

et al. 2016

Ann Clin Anal Med

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ÖzetAmaç: Tansiyonu normal olan üreme çağındaki polikistik over sendromlu (PKOS) kadınlarda sağ ve sol böbrek uzunluğu, parankim kalınlığı, renal arteriyel, venöz kan akımı ölçümlerinde farklılık olup olmadığını araştırmak. Gereç ve Yöntem: Rotterdam kriterlerine göre PKOS tanısı almış 40 kadın olgu ve 36 sağlıklı kadın olgu çalışmaya dahil edildi. Hormonal, biyokimyasal analiz, renal Doppler ultrasonografi yapıldı, sağ ve sol böbrek uzunluğu, parankim kalınlığı, pik sistolik velosite (PSV), rezistiv indeks (RI) ,venöz impedans indeksi(VI), insülin rezistansı, bozulmuş glikoz toleransı, serum lipid konsantrasyonu araştı-rıldı. Student t testi ve pearson korelasyon testi istatistik analiz için kullanıl-dı. Bulgular: Böbreklerin ölçümleri açısından PKOS'lu ve sağlıklı kadınlar arasında fark yoktu. Ana renal arterin pik sistolik velositesi PKOS'lu grupta daha düşüktü. Ana renal venöz impedans PKOS'lu grupta kontrol grubundan daha yüksekti. Ana renal rezistif indeks PKOS'lu grupta daha yüksekti, fakat istatistiksel olarak önemli değildi. Tüm olguları içeren bivariate analizde, ana böb-rek uzunluğu, ana parankim kalınlığı ölçümleri ile BMI, bel kalça oranı, serum açlık glikoz, insülin, LDL, tirgliserit seviyeleri pozitif ilişkiliydi. Tartışma: Biz PKOS'lu normotansif üreme çağındaki kadınlarda böbrek kan akımında deği-şiklikler olduğunu bulduk . Bu bulgular PKOS'un uzun önem renal ve kardiyovasküler komplikasyonlarının sonucunu gösteriyor olabilir. Anahtar KelimelerDoppler Ultrasonografi; Polikistik Over Sendromu Abstract Aim: To investigate whether there is alteration both right and left kidney lenght, parenchymal thickness, renal arterial,venous blood flow measurements in normotensive reproductive age women with polycystic ovary syndrome (PCOS). Material and Method: Forty women with PCOS according to Rotterdam criteria and thirty-six healthy volunteers women were included in our study. Hormonal, biochemical analysis, renal Doppler ultrasonography were performed and were investigated in terms of both left and right renal lenght, parenchymal thickness, peak systolic velocity (PSV), resistive index (RI), venous impedance index (VI), metabolic characteristics having insulin resistance, impaired glucose tolerance, serum lipid concentration. The student t test and pearson corelation test were used for statistical analysis. Results: The measurements for kidneys were not different between women with PCOS and healthy women. The peak systolic velocity of mean renal artery was lower in PCOS group. The mean renal venous impedance also was higher in PCOS group than control group. The mean renal resistive index was slightly higher in PCOS but not statistical significant. In bivariate corelation analyse including all patients, it was seen that BMI, WHR, level of serum fasting glucose, insulin, LDL, trigliserides were positively related with mean renal length and mean parenchymal thickness measurements. Discussion: We found that there was alterations kidney blood flow in normotensive reproductive age women with PCOS. This findings...

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Correlation of renal histopathology with sonographic findings

Abstract: Cortical echogenicity is the sonographic parameter that correlates best with renal histopathology. Although size or echogenicity alone are poor predictors of chronic irreversible disease, the likelihood of treatable disease in small kidneys with increased cortical echogenicity is very low.

Cited by 176 publications

References 13 publications

Renal Relevant Radiology

Renal Relevant Radiology

Doppler ultrasound and renal artery stenosis: An overview

Polycystic Ovary Syndrome: The Correlation Between Renal Doppler Ultrasound and Laboratory Parameters

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