Correlation of overweight condition and obesity with mortality by COVID-19 in Brazil's state capitals

Carneiro, Raquel Alencastro Veiga Domingues; Hillesheim, Danúbia; Hallal, Ana Luiza Curi

doi:10.20945/2359-3997000000351

Cited by 9 publications

(9 citation statements)

References 17 publications

(20 reference statements)

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“…In our study, there was correlation between the prevalence of obesity and COVID-19 mortality, i.e., as the obesity prevalence increased, the COVID-19 mortality rates increased in the population aged ≥ 15 years. These findings are consistent with correlational studies which found that, as the obesity prevalence increased, the COVID-19 deaths increased [ 10 , 11 , 12 , 13 ]. Cohort studies and meta-analyses on the effect of excess weight on COVID-19 clinical outcomes also reported that obesity was independently associated with the severity of COVID-19 and the risk of death increased [ 7 , 8 ].…”

Section: Discussionsupporting

confidence: 91%

“…Avoiding this bias, one recent study showed that excess weight linearly increased the risk of severe COVID-19, leading to admission to hospital and death (body mass index > 28 kg/m 2 ) [ 9 ]. In other observational studies, obesity prevalence was significantly correlated with both infection and/or COVID-19 mortality [ 10 , 11 , 12 , 13 ]. Despite these findings, to date, there is a gap of epidemiological data on obesity and COVID-19 mortality in low- and middle-income countries.…”

Section: Introductionmentioning

confidence: 89%

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Association between Obesity and COVID-19 Mortality in Peru: An Ecological Study

et al. 2021

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There is a gap in the epidemiological data on obesity and COVID-19 mortality in low and middle-income countries worst affected by the COVID-19 pandemic, including Peru. In this ecological study, we explored the association between body mass index (BMI), the prevalence of overweight and obesity, and the COVID-19 mortality rates in 25 Peruvian regions, adjusted for confounding factors (mean age in the region, mean income, gender balance and number of Intensive Care Unit (ICU) beds) using multiple linear regression. We retrieved secondary region-level data on the BMI average and prevalence rates of overweight and obesity in individuals aged ≥ 15 years old, from the Peruvian National Demographics and Health Survey (ENDES 2020). COVID-19 death statistics were obtained from the National System of Deaths (SINADEF) from the Peruvian Ministry of Health and were accurate as of 3 June 2021. COVID-19 mortality rates (per 100,000 habitants) were calculated among those aged ≥ 15 years old. During the study period, a total of 190,046 COVID-19 deaths were registered in individuals aged ≥ 15 years in 25 Peruvian regions. There was association between the BMI (r = 0.74; p = 0.00001) and obesity (r = 0.76; p = 0.00001), and the COVID-19 mortality rate. Adjusted for confounding factors, only the prevalence rate of obesity was associated with COVID-19 mortality rate (β = 0.585; p = 0.033). These findings suggest that as obesity prevalence increases, the COVID-19 mortality rates increase in the Peruvian population ≥ 15 years. These findings can help to elucidate the high COVID-19 mortality rates in Peru.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 89%

Association between Obesity and COVID-19 Mortality in Peru: An Ecological Study

et al. 2021

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“…They observed that among a list of 15 diseases considered risk conditions for severe COVID-19, cardiovascular diseases and obesity were the most frequent chronic conditions [4]. Carneiro et al, 2021 observed a positive correlation between the prevalence of overweight/obesity and the overall mortality due to COVID-19 in 26 state capitals and the Federal District of Brazil [9]. Takemoto et al, 2020 showed a high incidence of peri-obstetric mortality due to COVID-19 in Brazil and uncovered obesity as a risk factor [10].…”

Section: Resultsmentioning

confidence: 99%

The intersection between COVID-19 and obesity in the context of an emerging country

Pinhel

Watanabe

Noronha

et al. 2021

Clinical Nutrition ESPEN

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Background & Aims The worldwide outbreak of the coronavirus disease 2019 (COVID-19) has already caused a substantial public health burden. Increasing numbers of studies linked obesity to more severe COVID-19 consequence and mortality, challenging health systems worldwide, especially in emerging countries like Brazil. Herein, we aimed to search the literature and present the current intersection between obesity and COVID‐19 in the Brazilian population. Methods One hundred twenty-five articles were initially searched after duplicate removal, and nine were finally included in our analysis. Results Our findings emphasized the magnitude of COVID-19 infection in Brazil and the impact of obesity as a risk factor that aggravates the prognosis of outpatients or hospitalized patients. We also demonstrated social aspects of COVID-19 that could act enhancing the obesity condition in Latin American countries. Conclusions A more careful look at the available data could help to understand better the dynamic between obesity and COVID‐19, focusing on the Brazilian population and could eventually guide management strategies and therapies for COVID‐19 in the future.

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“…A high risk of death was found in males and younger patients with increased BMI [41], with a statistically significant association between the obesity prevalence and the mortality rate [48]. In addition, Bello-Chavolla et al showed that obesity increased the risk of mortality [42], and the rate of ICU admission is directly proportional to the BMI class [44,50].…”

Section: Discussionmentioning

confidence: 99%

Obesity Impact on SARS-CoV-2 Infection: Pros and Cons “Obesity Paradox”—A Systematic Review

Vulturar

Crivii

Orășan

et al. 2022

JCM

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Background: During the last years, the COVID-19 pandemic meets the pandemic generated by obesity, raising many questions regarding the outcomes of those with severe forms of infection. Methods: The present systematic review summarises and analyses the data providing evidence for or against the “obesity-paradox” in COVID-19 patients. After applying the inclusion and exclusion criteria, 23 studies were included. We also analysed the presumably underlying basic mechanisms. Results: The patients with a body mass index (BMI) of 30–40 kg/m2 presented severe symptoms that led to intensive care unit (ICU) admission but not increased death rate. Those with a higher degree of obesity, with a BMI higher than 40 kg/m2, led to a rise in the death rate, particularly in young patients. Obesity was associated with a higher rate of ICU admission but was not determined as an independent predictor of increased mortality. In contrast, some studies suggest a strong association between obesity or morbid obesity and the risk of death. Conclusions: The existence of “obesity-paradox” cannot be stated; our study presents obesity as a critical risk factor in the evolution of COVID-19.

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Correlation of overweight condition and obesity with mortality by COVID-19 in Brazil's state capitals

Cited by 9 publications

References 17 publications

Association between Obesity and COVID-19 Mortality in Peru: An Ecological Study

Association between Obesity and COVID-19 Mortality in Peru: An Ecological Study

The intersection between COVID-19 and obesity in the context of an emerging country

Obesity Impact on SARS-CoV-2 Infection: Pros and Cons “Obesity Paradox”—A Systematic Review

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