Correlation of N30 somatosensory evoked potentials with spasticity and neurological function after stroke: A cross-sectional study

Chen, Lilin; Li, Weijie; Cheng, Shimei; Liang, Shouyi; Huang, Mudan; Lei, Tingting; Hu, Xiquan; Liang, Zhenhong; Zheng, Huiru

doi:10.2340/16501977-2867

Cited by 2 publications

(2 citation statements)

References 39 publications

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“…Some studies found that early patients with stroke had predominantly axonal damage, manifested by a decreased N20 amplitude. The reason why the N20 latency was not correlated with the sensory function was that there were fewer stroke patients with demyelinating changes ( Wang et al, 2012 ; Chen et al, 2021 ; Yoon et al, 2021 ). Al-Rawi et al (2009) showed that the N20 amplitude correlated with the Medical Research Council score and could represent the level of function in patients with stroke, which was consistent with the results of this study.…”

Section: Discussionmentioning

confidence: 99%

Which sites better represent the sensory function of hands in convalescent stroke patients? A study based on electrophysiological examination

Liu

et al. 2023

Front. Neurosci.

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BackgroundAssessing hand sensation in stroke patients is necessary; however, current clinical assessments are time-consuming and inaccurate.ObjectiveThis study aimed to explore the nature of light touch sensation and two-point discrimination (2-PD) of different hand sites in convalescent stroke patients based on somatosensory evoked potentials (SEP).MethodsLight touch sensation and 2-PD of the thumb, the index finger, the little finger, thenar, and hypothenar were measured (n = 112) using sensory measurement tools. Sensory differences among the hand sites were then compared. The correlation analysis between SEP and the hemiplegic hand function was made. Sensory functions were divided into three levels: sensory intactness, sensory impairment, and sensory loss.ResultsLight touch sensations were mainly associated with sensory impairment in the finger and palm region. The 2-PD of the finger region was mainly sensory loss and that of the palm region was mainly sensory impairment. There was no statistical difference in the light touch sensation among the sites of the hand. The correlation coefficients between the 2-PD and SEP N20 amplitudes differed. The correlation coefficients of the thenar and hypothenar were the smallest, and that of the finger was the largest. Light touch sensation and 2-PD in patients with stroke were related to the hemiplegic hand function.ConclusionAny site on the hand could be selected as the measurement site for light touch sensation. The little finger and hypothenar may be appropriate sites when screening for 2-PD. To improve the patient’s recovery they could receive more sensory stimulation of the hand.

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Section: Discussionmentioning

confidence: 99%

Which sites better represent the sensory function of hands in convalescent stroke patients? A study based on electrophysiological examination

Liu

et al. 2023

Front. Neurosci.

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“…It has the advantages of high sensitivity, strong specificity, and repeatability ( 28 ). As an objective test, it excludes the influence of patient's subjective factors, which makes the evaluation results more reliable; SEP not only provides an objective assessment of stroke limb sensory function and feedback on the therapeutic effect of limb rehabilitation, but also guides the formulation of limb rehabilitation protocols and clinical treatment, and is considered an important reference indicator for predicting the prognosis of stroke limb function ( 29 , 30 ). The main observations of SEP are latency and wave amplitude, with latency related to the brain white matter and wave amplitude related to axons and cortex.…”

Section: Methodsmentioning

confidence: 99%

Effects of acupuncture synchronized rehabilitation therapy on upper limb motor and sensory function after stroke: a study protocol for a single-center, 2 × 2 factorial design, randomized controlled trial

Yu,

Yang,

Qin

et al. 2023

Front. Neurol.

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BackgroundUpper limb function reconstruction has been an important issue in the field of stroke rehabilitation. Due to the complexity of upper extremity dysfunction in stroke patients, the clinical efficacy produced by central or peripheral stimulation alone is limited. For this reason, our group has proposed acupuncture synchronized rehabilitation therapy (ASRT), i.e., simultaneous scalp acupuncture and intradermal acupuncture during rehabilitation. Pre-experiments results showed that this therapy can effectively improve the motor and sensory functions of upper limbs in post-stroke patients, but the clinical efficacy and safety of ASRT need to be further verified, and whether there is a synergistic effect between scalp acupuncture and intradermal acupuncture also needs to be studied in depth. Therefore, we designed a randomized controlled trial to compare the efficacy and safety of different therapies to explore a more scientific “synchronous treatment model.”MethodsThis is a single-center, randomized controlled trial using a 2 × 2 factorial design. We will recruit 136 stroke survivors with upper extremity dysfunction and randomize them into four groups (n = 34). All subjects will undergo routine treatment, based on which the Experimental Group 1: rehabilitation training synchronized with intradermal acupuncture treatment of the affected upper limb; Experimental Group 2: rehabilitation training of the affected upper limb synchronized with focal-side scalp acupuncture treatment, and Experimental Group 3: rehabilitation training synchronized with intradermal acupuncture treatment of the affected upper limb synchronized with focal-side scalp acupuncture treatment; Control Group: rehabilitation training of the affected upper limb only. The intervention will last for 4 weeks, 5 times a week. Both acupuncture treatments will be performed according to the Revised Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA). The primary outcome indicators for this trial are Fugl-Meyer Assessment-Upper Extremity and Somatosensory Evoked Potential. Secondary outcome indicators include Wolf Motor Function Test, Upper Extremity Function Test, revised Nottingham Sensory Assessment Scale, Diffusion Tensor Imaging, and Modified Barthel Index. The incidence of adverse events will be used as the indicator of safety.DiscussionThe study will provide high-quality clinical evidence on whether ASRT improves upper limb motor and sensory function and activities of daily living (ADL) in stroke patients, and determine whether scalp acupuncture and intradermal acupuncture have synergistic effects.Clinical trial registrationhttps://www.chictr.org.cn/, Chinese Clinical Trial Registry [ChiCTR2200066646].

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Correlation of N30 somatosensory evoked potentials with spasticity and neurological function after stroke: A cross-sectional study

Cited by 2 publications

References 39 publications

Which sites better represent the sensory function of hands in convalescent stroke patients? A study based on electrophysiological examination

Which sites better represent the sensory function of hands in convalescent stroke patients? A study based on electrophysiological examination

Effects of acupuncture synchronized rehabilitation therapy on upper limb motor and sensory function after stroke: a study protocol for a single-center, 2 × 2 factorial design, randomized controlled trial

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