Correlation of Lipid Profile with Duration of Diabetes and HbA1c Levels in Type 2 Diabetes Mellitus Patients: A Descriptive Cross-sectional Study

Priya, S; Begum, Nasreen

doi:10.5005/jp-journals-10082-02234

Cited by 2 publications

(1 citation statement)

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“…A significant positive correlation was also found between FBs, HBA1c level, and Duration of DM (r = 0.155, p-value = 0.005, r = 0.160, p-value = 0.004), as well as a significant negative correlation between total cholesterol, HDL-C, LDL-C, and Duration of DM (r = -0.152, p-value = 0.006, r = -0.145, p-value = 0.040, r = -0.113, p = 0.040. This result is similar to another result from a study carried out by Priya and Begum (2020), which found a substantial positive link between HBA1c, total cholesterol, LDL-C, and duration of diabetes, but a significant negative correlation between HDL-C and duration of diabetes (Priya and Begum, 2020).…”

Section: Discussionsupporting

confidence: 90%

Plasma glucose, HbA1c, insulin and lipid profile in Sudanese type 2 diabetic patients with cardiovascular disease: a case control study

et al. 2022

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Background: Type 2 diabetes mellitus (T2DM) and its consequences are a serious global public health issue. By 2030, the number of people with type 2 diabetes is predicted to reach 439 million. The purpose of this study is to evaluate the plasma levels of glucose, HbA1c, insulin, and lipid profile in Sudanese T2DM patients. Methods: This case control study included 165 Sudanese patients with diabetic type 2 and a cardiovascular condition as cases and 165 diabetic type 2 volunteers without a cardiovascular disorder as controls. The concentrations of plasma glucose, HbA1c, and lipid profile were assessed using a Mindray BS-480 auto-chemistry analyzer, and insulin was analyzed using a Cobase 411 auto analyzer. The collected data were analyzed using statistical tools for social science computer programs (SPSS version 21). Results: According to the findings, (59.4 %) of patients between the ages of (50-69). Females made up 50.9 %. (38.2 %) of patients had an illness duration of between (8-15 years). (41.8%) of individuals did not have hypertension. There was a substantial rise in BMI, FBG, HbA1c, HDL-C, and insulin among diabetics with cardiovascular disease compared to diabetics without cardiovascular disease (p-value = 0.001, 0.000, 0.018, and 0.000). Females had significantly higher blood TC, LDL-C, HDL-C, and BMI than males (p-values = 0.000, 0,001, and 0.000, respectively). There were significant positive correlation between FBS, HBA1c, insulin and duration of disease (r=0.155, p, value=0.005) (r=0.160, p, value=0.004)(r=0.103, p. value=0.061)respectively, while there were significant negative correlation between TC, TG,LDL-C, HDL-C and duration of disease (r=-0.152, p, value= 0.006)(r=-0.023, p, value=0.678)(r=-0.113, p, value= 0.040)(r=-0.145, p, value=0.008)respectively. Conclusion: When comparing diabetics with cardiovascular disease to diabetics without cardiovascular disease, there was a substantial rise in BMI, FBG, HbA1c, HDL-C, and insulin. FBS, HBA1c, insulin, and illness duration all had a strong positive connection.

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Section: Discussionsupporting

confidence: 90%