Correlation of Lipid Profile and Glycemia in Oral Precancerous Lesion and Conditions

Mujoo, Sheetal; Shashikant, M.C.; Dubey, A. K.

doi:10.20530/ijta_33_119-128

Cited by 2 publications

(3 citation statements)

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“…In the present study, a significant decrease was noticed in serum HDL in the study group of patients as compared to the control group. Similar findings were reported by Mujooet al [33], Anand et al [34], Meisel et al [35], and Granero Fernandez et al [36] in their studies to assess alterations in lipid profile levels.…”

Section: Discussionsupporting

confidence: 88%

“…In the present study, serum LDL and serum VLDL levels were significantly lower when compared with the control group, whereas the difference was not statistically significant in the studies done by Mujoo et al [33] and Chalkoo et al [37] While Subbulakshmi et al stated that the decrease in serum LDL and VLDL in squamous cell carcinoma cases may be due to enhanced lipid peroxidation due to decline in antioxidants [38].…”

Section: Discussioncontrasting

confidence: 72%

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A Comparative Study of Serum Lipid Profile in Patients with Oral Squamous Cell Carcinoma and Healthy Population in a Tertiary Health Care Centre in North-Western India

Khyalia

2022

Asian Pac J Cancer Biol

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Aims and Objectives: The aim of the study was to study serum lipid profile in patients with oral squamous cell carcinoma (OSCC) and to compare their levels with those of healthy population. Materials and Methods: This study was done in forty five patients of Oral Squamous Cell Carcinoma and the results were compared with results of forty five age and sex matched healthy controls . Serum obtained from centrifugation of 12 hour fasting blood samples was analyzed on fully automated analyzer Beckman coulter AU-680 for estimating the lipid levels (cholesterol, triglycerides [TGL], and high-density lipids [HDL]) by colorimetric method. Low-density lipid [LDL] values were obtained by calculator. Results: The comparison of lipid profile levels between Oral Squamous Cell Carcinoma cases and healthy controls shows statistically significant results for TC, HDL and LDL. Conclusion: The change in lipid levels may have an early diagnostic or prognostic role in oral malignant lesions and can be used as a biomarker for OSCC patients.

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Section: Discussionsupporting

confidence: 88%

Section: Discussioncontrasting

confidence: 72%

A Comparative Study of Serum Lipid Profile in Patients with Oral Squamous Cell Carcinoma and Healthy Population in a Tertiary Health Care Centre in North-Western India

Khyalia

2022

Asian Pac J Cancer Biol

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“…23 In another study, Mujoo et al in another study while comparing lipid levels among cases of OSMF and leukoplakia found the lipid profile of two precancerous lesions to be comparable but found that combined precancerous group had significantly lower TC and TG levels as compared to controls. 24 However, the present study highlighted certain limitations and shortcomings in evaluation of such relationship such as need of a purposive sampling design, adequate number of cases for each type of oral precancerous lesion, histopathological, clinical, demographic, anthropometric and dietary details in order to examine this relationship in a better way. The findings of present study showed that lipid levels in patients with precancerous oral lesions are generally of lower order.…”

Section: Discussionmentioning

confidence: 91%

Correlation between plasma lipid levels in patients with different oral pre-cancerous lesions

Goyal

Srivastava

Jafar

et al. 2021

Int J Otorhinolaryngol Head Neck Surg

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Background: Oral precancerous lesions could be defined as the lesions present in oral cavity that have a potential to become cancer. Recognition of precancerous lesions has its own significance as it helps in early detection of risk of cancer which in itself is quite useful for formulating appropriate preventive strategies that could assure better survival rates. The aim of the study was to assess the correlation of lipid levels in patients with different oral precancerous lesions.Methods: A total of 150 patients with oral lesions attending the department of otorhinolaryngology at Era’s Lucknow Medical college and Hospital, Lucknow, were included in the study. A biopsy specimen was taken from each patient along with 5 ml fasting blood sample for serum lipid estimation which was done by dry chemistry Chemino Heinz method. Results: A total of 150 patients with age ranging from 13-70 years and a male is to female ratio of 1.68 was studied. Burning sensation was the most common symptom and OSMF being the most common diagnosis. All the components of lipid profile except HDL of patients with different histopathological diagnosis were found to be comparable. No association of derangement in any of the components of lipid levels and histopathological diagnosis was observed.Conclusions: The findings of present study showed that lipid levels in patients with precancerous oral lesions are generally of lower order. However, the present study could not assess a significant association between lipid levels and different types of oral premalignant lesions.

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Correlation of Lipid Profile and Glycemia in Oral Precancerous Lesion and Conditions

Cited by 2 publications

References 17 publications

A Comparative Study of Serum Lipid Profile in Patients with Oral Squamous Cell Carcinoma and Healthy Population in a Tertiary Health Care Centre in North-Western India

A Comparative Study of Serum Lipid Profile in Patients with Oral Squamous Cell Carcinoma and Healthy Population in a Tertiary Health Care Centre in North-Western India

Correlation between plasma lipid levels in patients with different oral pre-cancerous lesions

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