Correlation of Intraocular Pressure Between Both Eyes After Bilateral Selective Laser Trabeculoplasty in Open-angle Glaucoma

Lee, Jacky; Wong, Mandy O. M.; Wong, Raymond Siu Ming; Lai, Jimmy S. M.

doi:10.1097/ijg.0000000000000274

Cited by 17 publications

(12 citation statements)

References 28 publications

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“…26 In addition, Lee et al demonstrated that IOP response in both eyes was correlated after bilateral SLT. 27 In our study, we also demonstrated that significant correlations of both IOP responses to SLT exist at 1 month and 6 months postoperative. We speculated that this might be because both eyes have similar function and TM structure.…”

Section: Volume 6 | Number 1 2017supporting

confidence: 76%

Predictive Factors Associated with Short-term and Long-term Outcomes of Half Angle Selective Laser Trabeculoplasty

Han

Suh

Kim

et al. 2017

J Korean Glaucoma Soc

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Purpose: To evaluate the diagnostic capability of quantified optic nerve head (ONH) depth analysis system incorporated in the Nonmyd-WX 3D retina camera (Kowa, Tokyo, Japan) in discriminating between glaucoma suspects and glaucoma subjects. Methods: The present study included the eyes with unilateral or bilateral primary open angle glaucoma (POAG) using maximal dose glaucoma medications. Success was defined as an intraocular pressure (IOP) reduction ≥ 20% compared to baseline. To investigate the factors associated with short-term and long-term response to SLT, univariate and multivariate logistic regression analyses using a generalized estimating equation model were performed. Results: In this study, 184 eyes in 147 patients were included. In multivariate analysis, higher baseline IOP was associated with positive short-term and long-term response (p = 0.026; p = 0.019, respectively). Secondary treatment was associated with negative short-term and long-term response in multivariate analysis (p = 0.006; p = 0.008, respectively). Severe trabecular meshwork (TM) pigmentation was associated with positive short-term response (p = 0.019). The correlation between IOP responses in both eyes was significant at 1 month and 6 months postoperatively (p < 0.001; p = 0.006, respectively). The correlation between IOP responses on primary and secondary half angle SLT treatments was significant at 3 months and 6 months postoperatively (p = 0.003; p = 0.005, respectively). Conclusions: Short-term and long-term outcomes of half angle SLT were positively associated with baseline IOP and negatively associated with secondary SLT treatment. Severe TM pigmentation was positively associated with short-term response of SLT. IOP response correlations between bilateral treatment cases and between primary and secondary SLT were significant.

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Section: Volume 6 | Number 1 2017supporting

confidence: 76%

Predictive Factors Associated with Short-term and Long-term Outcomes of Half Angle Selective Laser Trabeculoplasty

Han

Suh

Kim

et al. 2017

J Korean Glaucoma Soc

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“…Previous studies suggest that SLT has a greater effect when higher energy (Ayala & Chen ) and a greater amount of laser spots (Lee et al. ) are used during the procedure. Since we found no difference between residents and specialists, who used the same treatment regime, but a significant difference between these groups and senior specialists who used more laser spots and energy during treatment, the data would suggest that experience is not the deciding factor in terms of outcome and IOP reduction.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of selective laser trabeculoplasty as an intraocular pressure lowering option

Belitsky

Škiljić

Zetterberg

et al. 2019

Acta Ophthalmologica

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Purpose Selective laser trabeculoplasty (SLT) is one of the many treatment options for lowering intraocular pressure (IOP) in patients with glaucoma. This study aimed to evaluate the effect of SLT. Methods Data were collected from medical records of 289 patients who underwent SLT treatment (180° of trabecular meshwork) during 2014 and 2015 at the Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, Sweden. Baseline characteristics and information from a follow‐up within 100 days were also recorded. The study analysed different subtypes of glaucoma with regard to SLT, with a particular focus on exfoliative glaucoma, a common subtype in Sweden. Successful treatment was defined as an IOP lowering effect of >20% with no further changes in treatment. The impact of surgeon's experience on treatment outcome was also analysed. Results Both patients with exfoliative glaucoma and those with primary open‐angle glaucoma showed a reduction in mean IOP; no significant difference was found between these two subtypes before treatment or at the first follow‐up. The success rate at follow‐up (within 100 days) was 52%. There was a significant difference in outcome between surgeons with different levels of experience, but this difference could likely be explained by differences in treatment strategies and total energy used. Conclusion For many patients with glaucoma, SLT was an effective treatment option for lowering IOP. It was also effective for several glaucoma subtypes. However, not all patients had a significant reduction in IOP after treatment with SLT, and some may require additional treatment.

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“…Interestingly, if success was achieved in one eye but not in the fellow eye, there was strong negative correlation between the two eyes. In the majority of eyes, the success or non-success of one eye may predict the clinical outcome of the fellow eye [32]. …”

Section: Surgical Techniquementioning

confidence: 99%

A Review of Selective Laser Trabeculoplasty: Recent Findings and Current Perspectives

Zhou

Aref

2017

Ophthalmol Ther

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Selective laser trabeculoplasty (SLT) has been widely used in the clinical management of glaucoma, both as primary and adjunctive treatment. As new evidence continues to arise, we review the current literature in terms of indications and efficacy, surgical technique, postoperative care, repeatability, and complications of this therapy. SLT has been shown to be effective in various glaucomas, including primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), steroid-induced glaucoma, pseudoexfoliation glaucoma (PXFG), and primary angle-closure glaucoma (PACG), as well as other glaucoma subtypes. Relatively high preoperative intraocular pressure (IOP) may predict surgical success, while other parameters that have been studied do not seem to affect the outcome. Different techniques for performing the procedure have recently been explored, revealing that minor modifications may lead to a more favorable or safer clinical outcome. The utilization of postoperative medications remains controversial based on the current evidence. A short-term IOP increase may complicate SLT and can also persist in certain cases such as in exfoliation glaucoma. The efficacy and safety of repeat SLT are shown in multiple studies, and the timing of repeat procedures may affect the success rate.

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Correlation of Intraocular Pressure Between Both Eyes After Bilateral Selective Laser Trabeculoplasty in Open-angle Glaucoma

Abstract: There is a strong and significant correlation in the IOP-lowering response to SLT between both eyes in near 80% of treated OAG subjects, whereas near 20% had an asymmetrical and inverse response to SLT between both the eyes.

Cited by 17 publications

References 28 publications

Predictive Factors Associated with Short-term and Long-term Outcomes of Half Angle Selective Laser Trabeculoplasty

Predictive Factors Associated with Short-term and Long-term Outcomes of Half Angle Selective Laser Trabeculoplasty

Evaluation of selective laser trabeculoplasty as an intraocular pressure lowering option

A Review of Selective Laser Trabeculoplasty: Recent Findings and Current Perspectives

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