Correlation of Internet Addiction Disorder with Level of Stress and BDNF Gene (Val66Met) Polymorphism among Medical Students in Malaysia

Al-Hatamleh, Mohammad A. I.; Al-Shajrawi, Omar Mahmoud; Khan, Saif Ullah; Nadeem, Muhammad Ilyas; Simbak, Nordin; Latif, Adibah Abdul; Baig, Atif Amin; Ariff, Tengku Mohammad

doi:10.5958/0974-360x.2018.00700.x

Cited by 2 publications

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“…Although there is still a lack of studies on stress among Malaysian medical students, previous studies have described the Malaysian medical schools as an environment characterised with extra stressful circumstances,11, 12, 13 which often has an adverse effect on students' mental, and consequently, physiological health. The estimated prevalence of emotional disorders related to high stress levels in medical students was found in several studies in Malaysia to be higher compared to the general population 14, 15, 16…”

Section: Introductionmentioning

confidence: 99%

The Brain-Derived Neurotrophic Factor (BDNF) gene Val66Met (rs6265) polymorphism and stress among preclinical medical students in Malaysia

Al-Hatamleh

Hussin

Taib

et al. 2019

Journal of Taibah University Medical Sciences

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ObjectiveThis study aimed to determine the allelic and genotypic association of the Val66Met (rs6265) polymorphism in the BDNF gene with stress levels in preclinical medical students of Universiti Sultan Zainal Abidin (UniSZA), Terengganu, Malaysia.MethodsIn this cross-sectional study, we recruited all 122 preclinical medical students. The validated depression anxiety stress scales-21 (DASS-21) questionnaire was distributed and blood samples were collected from each subject for DNA extraction. Genotyping analysis of the BDNF gene (Val66Met) polymorphism was performed via an optimised polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method.ResultsA total of 105 subjects agreed to participate in this study. Indian students were found to more likely have the Val/Val genotype, whereas Malay students were more likely to have the Met/Met genotype (p = 0.027). Individuals carrying any one of the three BDNF genotypes (Val/Val, Val/Met and Met/Met) differed significantly from each other in terms of their perception of stress (p = 0.010); students carrying the Val/Val genotype (M = 10.6) perceived significantly lower stress than students carrying the Val/Met (M = 14) and Met/Met (M = 15.1) genotypes.ConclusionIn our study, the Met-allele was associated with higher stress levels. To the best of our knowledge, this is the first study investigating this stress-related gene in medical students. The findings from this study should trigger more investigators to focus on the impact of stress on genetically predisposed medical students.

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Section: Introductionmentioning

confidence: 99%

The Brain-Derived Neurotrophic Factor (BDNF) gene Val66Met (rs6265) polymorphism and stress among preclinical medical students in Malaysia

Al-Hatamleh

Hussin

Taib

et al. 2019

Journal of Taibah University Medical Sciences

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Effectiveness of an Educational Intervention on Prevention of health problems due to Internet addiction among students of selected college of New Delhi

Shukla,

Goyal,

Biswas

2023

IJNER

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Internet Addiction (IA) has been recognized as a global concern that can lead to sedentary lifestyles and a decline in physical fitness. Digital eye strain, pain in the upper body parts, obesity, insomnia, anxiety, and depression are health problems commonly reported among internet users. There is more requirement for internet use among students owing to their educational or research needs. There is an urgent need to sensitize students about the health hazards due to IA and ways to prevent them. Thecurrent studyevaluates the effectiveness of educational intervention on the prevention of health problems due to internet addiction and to find out the association of post-test knowledge and practice score with selected demographic variables Quantitative Experimental research with one group Pre-test, and Post-test design was conducted at PGDAV College, New Delhi among 54 college students using total enumeration sampling. The t-value (18.39) and (14.76) between pre-test and post-test knowledge and practice scores were statistically significant at 0.05 level of significance. In the current study, the educational intervention was effective in enhancing the knowledge and practice expressed on the prevention of health problems due to internet addiction. A significant association was found between post-test knowledge scores and the academic year. However, no significant association was found between post-test practice scores and selected variables.

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Correlation of Internet Addiction Disorder with Level of Stress and BDNF Gene (Val66Met) Polymorphism among Medical Students in Malaysia

Cited by 2 publications

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The Brain-Derived Neurotrophic Factor (BDNF) gene Val66Met (rs6265) polymorphism and stress among preclinical medical students in Malaysia

The Brain-Derived Neurotrophic Factor (BDNF) gene Val66Met (rs6265) polymorphism and stress among preclinical medical students in Malaysia

Effectiveness of an Educational Intervention on Prevention of health problems due to Internet addiction among students of selected college of New Delhi

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