Correlation of histologic subtypes of primary basal cell carcinoma and number of Mohs stages required to achieve a tumor-free plane

An Overview on Basal Cell Carcinoma

“…Also, BCCs with aggressive histologic patterns require more aggressive treatment; in addition, when the Mohs micrographic surgical technique is used, a greater number of stages are required to achieve tumor free margins as compared with BCCs without aggressive tumor growth patterns (99). Inadequate treatment of BCCMH may represent an unsuspected etiology for recurrent skin cancer.…”

Basal cell carcinoma and World War II–era cathode ray oscilloscope exposure

“…24 This increase in layers required to achieve a tumor-free plane indicates an increase in subclinical spread of the tumors. [23][24][25] In addition, it is important to note that of the 30 BCCs that required 3 or more Mohs layers to obtain tumor-free margins, 10 were aggressive subtypes, and that all but 4 of the 30 BCCs that required 3 or more Mohs layers were smaller than 1 cm in diameter on initial clinical examination (with 8 of the lesions less than 0.5 cm). The final tumor-free margined defects that resulted from these clinically small lesions averaged 1.6 3 2.1 cm, further indicating considerable subclinical extension of the tumors.…”

“…We propose that MMS may be a superior therapeutic option to remove these aggressive tumors and avoid incomplete resection through methods such as curettage, cryotherapy, or wide excision. 23,[25][26][27] In addition, we would recommend scheduling more frequent check-up visits aimed at early nonmelanoma skin cancer detection in such patients.…”

Acurácia da biópsia incisional por trépano de 2 mm nos tumores palpebrais: estudo comparativo entre um e dois sítios

“…Dentre as técnicas de biópsia, destacamos: (19,20,(79)(80)(81) • Biópsia por "shave" (saucerização): rápida e não requer sutura; para lesões elevadas, superficiais e não pigmentadas, com suspeita de benignidade, pois a margem profunda poderá estar comprometida.…”

“…(19,20,(79)(80)(81) Dentre os motivos para a não concordância entre biópsia e anatomopatológico final, destacamos a ação inflamatória e cicatricial após a realização da biópsia, podendo até induzir regressão tumoral, e, nos casos de CBC, a presença de mais de um subtipo na maioria das lesões. …”