Correlation of heart rate and blood pressure variability as well as hs-CRP with the burden of stable coronary artery disease

Xiong, Peng; Peng, Dan; Hu, Yongjun; Huang, Gang; Tang, Shaoyong

doi:10.23736/s0026-4725.20.05153-1

Cited by 6 publications

(5 citation statements)

References 25 publications

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“…Plasma biomarkers, including not only traditional biomarkers like B type natriuretic peptide (BNP) [ 60 ] or troponin [ 18 ] but also inflammatory biomarkers as C -reactive protein (CRP) or high-sensitive CRP (hsCRP) [ 61 ], have improved CAD risk prediction. Moreover, researchers have investigated emerging biomarkers and further categories, such as inflammation (lpoprotein-associated phospholipase A2 [ 62 ], pentraxin-3 [ 63 ]), myocardial stress (soluble form of ST2 (18)), plaque stability (matrix metalloproteinase [ 64 ], transcription factor 3 [ 65 ], complement component 7 [ 66 ], OX40L and ICAM-1 [ 67 ]), myocardial fibrosis [ 68 , 69 ], RNA (circRNA [ [70] , [71] , [72] ], miRNA [ 73 , 74 ], mRNA [ 75 ]), and DNA (SNP[ 9 , 76 , 77 ], insertion/deletion [ 78 ]).…”

Section: Discussionmentioning

confidence: 99%

Characterization of global research trends and prospects on sudden coronary death: A literature visualization analysis

Luo¹,

Zhao²,

Chen³

et al. 2023

Heliyon

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Section: Discussionmentioning

confidence: 99%

Characterization of global research trends and prospects on sudden coronary death: A literature visualization analysis

Luo¹,

Zhao²,

Chen³

et al. 2023

Heliyon

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“…LDL‐C is considered to be a pivotal player in atherogenesis and is linked with an enhanced risk of CHD 10,37 . hs‐CRP has a high ability to identify the CHD risk groups and is significantly correlated with coronary lesions 38,39 . BNP is an acknowledged predictor of cardiovascular outcomes in CHD individuals 40 .…”

Section: Discussionmentioning

confidence: 99%

“…10,37 hs-CRP has a high ability to identify the CHD risk groups and is significantly correlated with coronary lesions. 38,39 BNP is an acknowledged predictor of cardiovascular outcomes in CHD individuals. 40 cTnI is a biochemical gold standard in the diagnosis of cardiac injury.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic value of peripheral blood miR‐296 combined with vascular endothelial growth factor B on the degree of coronary artery stenosis in patients with coronary heart disease

Wang

et al. 2023

J of Clinical Ultrasound

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Objective Coronary heart disease (CHD) is a disorder resulting from organic and functional coronary artery stenosis (CAS), thus causing reduced oxygenated blood in the heart. miRNAs are useful biomarkers in the diagnosis of atherosclerosis, CHD, and acute coronary syndrome. Vascular endothelial growth factor (VEGF) is closely related to CHD. This study explored the correlation of miR‐296 and VEGF‐B expression levels in peripheral blood with CAS degree in CHD patients. Methods Totally 220 CHD patients were enrolled and classified into mild‐(71 cases)/moderate‐(81 cases)/severe‐CAS (68 cases) groups, with another 80 healthy cases as controls. The serum miR‐296 and VEGF‐B expression levels were detected using reverse transcription quantitative polymerase chain reaction. The correlation between miR‐296 and CAS‐related indexes was assessed via Pearson analysis. The binding relationship of miR‐296 and VEGF‐B was first predicted and their correlation was further analyzed via the Pearson method. The clinical diagnostic efficacy of miR‐296 or VEGF‐B on CAS degree was evaluated by the receiver operating characteristic curve. Results Serum miR‐296 was downregulated in CHD patients and was the lowest in patients with severe‐CAS. miR‐296 was negatively‐correlated with high‐sensitivity C‐reactive protein, brain natriuretic peptide, and cardiac troponin I. miR‐296 targeted VEGF‐B. VEGF‐B was upregulated in CHD patients and inversely‐related to miR‐296. Low expression of miR‐296 and high expression of VEGF‐B both had high clinical diagnostic values on CAS degree in CHD patients. miR‐296 combined with VEGF‐B increased the diagnostic value on CAS. Conclusion Low expression of miR‐296 combined with high expression of its target VEGF‐B predicts CAS degree in CHD patients.

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“…Meanwhile, electrophysiological parameters, especially heart rate variability-related indicators SDNN, PNN50, SDANN, RMSSD and Hypersensitive C-reactive protein (hs-CRP), were significantly correlated with the degree of tubular artery lesions. Patients with elevated hs-CRP may have the chance of stable coronary artery disease (21). Studies have shown that CRP in acute coronary syndrome suffers is negatively correlated with SDNN and RMSSD, and ET-1 is negatively associated with low-frequency power components of TP and LF (22).…”

Section: Discussionmentioning

confidence: 99%

Relationship between dynamic electrocardiogram and CRP, IL-6, ET-1 expression in myocardial ischemia patients with coronary heart disease

Lin You

2023

Cell Mol Biol (Noisy-le-grand)

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Correlation of heart rate and blood pressure variability as well as hs-CRP with the burden of stable coronary artery disease

Cited by 6 publications

References 25 publications

Characterization of global research trends and prospects on sudden coronary death: A literature visualization analysis

Characterization of global research trends and prospects on sudden coronary death: A literature visualization analysis

Diagnostic value of peripheral blood miR‐296 combined with vascular endothelial growth factor B on the degree of coronary artery stenosis in patients with coronary heart disease

Relationship between dynamic electrocardiogram and CRP, IL-6, ET-1 expression in myocardial ischemia patients with coronary heart disease

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