Correlation of Haemoglobin level and Urine Albumin in relation to Glycated Haemoglobin in Type 2 Diabetes

Abstract

Background; Diabetes mellitus is a chronic metabolic disorder characterized by hypergycemia and derangement in protein and fat metabolism. The prevalence of diabetes was approximately 2.8% in 2000 and is estimated to grow to 4.4% by 2030 worldwide.The Aim and objective of the present study is to correlate haemoglobin , urine albumin with glycated haemoglobin also called as HbA1c testing. Methods:This study was conducted on 100 Diabetic patients without hypertension , coronary artery disease & pregnancy. Hb A1c was estimated in diabetic subjects using random EDTA samples by BIORAD D-10 ion exchange high performance liquid chromatography(HPLC), fasting blood glucose was by Glucose oxidase-peroxidase method and haemoglobin estimation by using automated analyzer sysmex XN 1000, Urine albumin measured with URODIP 10A Reagent strips . The data was analyzed by descriptive analysis. Result and Conclusion:Result shows that hemoglobin was significantly reduced in diabetic patients with high HbA1c and presence of urine albumin which is highly increased in diabetic patients with high glycated hemoglobin. Patients with poor glycemic control are at risk of developing nephropathy. This condition can be controlled by changes in lifestyle and frequent monitoring.