Correlation of gasdermin B staining patterns with prognosis, progression, and immune response in colorectal cancer
Liang Sun,
Jiahui Wang,
Yuxuan Li
et al.
Abstract:Background
Pyroptosis is a type of programmed cell death mediated by the gasdermin family. Gasdermin B (GSDMB), as a member of gasdermin family, can promote the occurrence of cell pyroptosis. However, the correlations of the GSDMB expression in colorectal cancer with clinicopathological predictors, immune microenvironment, and prognosis are unclear.
Methods
Specimens from 267 colorectal cancer cases were analyzed by immunohistochemistry to determin… Show more
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