Correlation of dyspeptic symptoms and endoscopic findings in diabetic patient

Abstract

Objective:We aimed to demonstrate the relationship between the endoscopically increased mucosal damage and the frequency of dyspeptic symptoms in patients with diabetes. Material and Methods:The 42 diabetic patients with dyspeptic complain and 40 healthy dyspeptic people were involved in this study and evaluated with video endoscopes.Results: Diabetic patients when compared with the control group according to the endoscopic evaluation and Glasgow Dyspepsia Symptom Scoring System no significant difference had been detected. The symptoms of the diabetic group and the control group were familiar and there was no significant difference between the frequencies of the symptoms in both groups. In dyspeptic diabetic patients a weak correlation between BMI and endoscopically detected hiatal hernia was reported. However there was no relation between BMI and the other gastrointestinal symptoms. Also there was no difference between the patients with neuropathy and without neuropathy in terms of endoscopic findings and gastrointestinal symptoms. Conclusion:Endoscopic findings of diabetic patient and non-diabetic control group were compared statistically. Although gastric ulcus was significantly higher in diabetic group, there was no significant difference between two groups in terms of other endoscopic findings. Hovewer, gastric ulcus frequency in diabetic group is higher, there were no significant difference in terms of gastrointestinal symptoms, diabetic complications and glisemic control in patients with other endoscopic lesions when compared with the patients with gastric ulcus. Hiatal hernia frequency in diabetic patients was higher due to control group. In shed light on our findings, diabetic patients must be evaluated for the esophageal reflux symptoms.

A relationship between endoscopic findings and diabetic regulation, and complications in patients with diabetes mellitus

“…Similar studies have demonstrated a relationship between dyspeptic complaints and diabetic regulation, with dyspeptic complaints being higher in DM patients with poor glycemic control [19,20]. In the study conducted by Oner et al, who investigated frequency of dyspeptic complaints among diabetic and non-diabetic patients, it was reported that dyspeptic complaints were significantly higher in DM patients [19]. Although dyspeptic complaints are frequent in DM patients, it is not clear whether there is any difference between non-diabetic patients in terms of endoscopic findings, with conflicting results reported [19][20][21][22].…”

“…Although dyspeptic complaints are frequent in DM patients, it is not clear whether there is any difference between non-diabetic patients in terms of endoscopic findings, with conflicting results reported [19][20][21][22]. In a comparison of endoscopic findings between two groups of patients, Oner et al showed that the frequency of gastric ulcers was higher in DM patients, but there was no significant difference in terms of other endoscopic findings [19]. Koch et al found no correlation between glycemic control and dyspeptic complaints and endoscopic findings [9].…”

“…In the study conducted by Oner et al, who investigated frequency of dyspeptic complaints among diabetic and non-diabetic patients, it was reported that dyspeptic complaints were significantly higher in DM patients [19]. Although dyspeptic complaints are frequent in DM patients, it is not clear whether there is any difference between non-diabetic patients in terms of endoscopic findings, with conflicting results reported [19][20][21][22]. In a comparison of endoscopic findings between two groups of patients, Oner et al showed that the frequency of gastric ulcers was higher in DM patients, but there was no significant difference in terms of other endoscopic findings [19].…”

“…Given the linear relationship between microvascular and macrovascular complications, and HbA 1c level, the American Diabetes Association (ADA) proposes to keep the target HbA 1c level below 7% [14][15][16][17][18]. Similar studies have demonstrated a relationship between dyspeptic complaints and diabetic regulation, with dyspeptic complaints being higher in DM patients with poor glycemic control [19,20]. In the study conducted by Oner et al, who investigated frequency of dyspeptic complaints among diabetic and non-diabetic patients, it was reported that dyspeptic complaints were significantly higher in DM patients [19].…”

Evaluation Conformity Rejimen Peptic Ulcer Drug Therapy In Inpatient Care Facility At West Nusa Tenggara Regional Public Hospital

“…Sedangkan untuk frekuensi kejadian ulkus pada komorbid hipertensi, diabetes dan CVD berhubungan dengan terapi pengobatan dari komorbid dimana penggunaan antiplatelet atau anti koagulan seperti, aspirin, cropidogel pada ke 3 komorbid tersebut dapat memicu kerusakan pada mukosa lambung (22), (23).…”