Correlation of Corneal Elevation With Severity of Keratoconus by Means of Anterior and Posterior Topographic Analysis

Abstract

Anterior and posterior corneal surface height data obtained by elevation-based tomography provide useful information in improving keratoconus diagnostic accuracy and in grading the severity of keratoconus.

Intereye Asymmetry Detected by Scheimpflug Imaging in Subjects With Normal Corneas and Keratoconus

“…In contrast, the mean posterior elevation between eyes with keratoconus was statistically significant; evidence that keratoconus is an asymmetric disease and posterior elevation is modified according to severity of the cone. 26 Our study does not attempt to establish the diagnosis based in this single metric but suggests that the evaluation of asymmetry in normal subjects and keratoconic patients should not be done only with anterior surface data; it should also include intereye asymmetry concerning pachymetry and posterior elevation data. When evaluating the distance and volume, the mean intereye asymmetry in distance from the TP to the apex of the cornea in the normal group was 0.27 mm and in the keratoconus group 0.22 mm.…”

Comparison of stromal corneal nerves between normal and keratoconus patients using confocal microscopy

“…[11][12][13][14] Confocal microscopy: At the corneal imaging unit of the Cornea and Refractive Surgery Department of the hospital of the Association to Prevent Blindness in Mexico, after topical anesthesia of cornea with tetracaine hydrochloride 5.0 mg per ml (Ponti Ofteno, Laboratorios Sophia, S.A. Guadalajara, Mexico), all study subjects in both groups underwent a central scan of the total cornea thickness using Confoscan 4 confocal microscope (Fortune Technologies, Vigonza, Italy). Each confocal microscopy test rendered scanned images in JPEG format, consisting of 2 consecutive scans of total central cornea thickness depth; this scan is equivalent to the endothelium and epithelium and back to endothelium imaging scan, i.e., from posterior to anterior and back to posterior, to allow movement in the Z axis of central cornea thickness.…”

Cross-Linking Treatment for Progressive Keratokonus

“…No complication reported 8 After that, cross-linking became a worldwide used technique. Later and latest study 16 , as the Siena Eye Study 14 , investigates long-term effects of standard cross-linking. Three hundred and sixty-three eyes were treated and monitored over 4 years, producing reliable long-term results proving the efficacy of the procedure in terms of long-term stability of the cornea by halting the progression of keratokonus, and proving the safety of the procedure 14 …”