Correlation of Allred Score with Tumor Behavior in Breast Cancer Patients Referred to Shahid-Mohammadi Hospital From 2010 to 2017

Abstract

Background: Breast cancer is one of the most common malignancies in women around the world, which makes it essential to identify the behavior of tumors regarding cost-effectiveness and highly diagnostic methods. Objectives: The aim of this study was to determine the relationship between Allred score and tumor behavior in breast cancer patients. Methods: This study was performed on 100 patients with breast cancer. The following data were obtained for each participant: Patient satisfaction and demographic data, tumor size, tumor grade, lymph node involvement and histology of tumor, and Allred score. Chi-square, T student and analysis of variance (ANOVA) tests were used to compare the data. Results: The results of this study showed that Allred score based on PR and ER had a reverse and significant correlation with tumor size (P < 0.05). On the other hand, Allred negative findings were found to be higher in patients with lymph nodes involvement (P < 0.05). Conclusions: Considering the benefits and potentials of Allred score based on PR and ER in detecting tumor behavior and according to the high prevalence of breast cancer, it is suggested for the results of this study to be provided to specialists from different health centers to improve the correct prediction of tumor behavior.