Correlation between smoking status, periodontitis and SIgA level in a sample of patients

Abstract

Periodontitis is one of the most highly prevalent chronic diseases worldwide. Periodontal disease, along with severe dental caries, causes tooth loss, which result in reduced functional capacity, selfesteem and social relationships. Hence, it affects people's quality of life .Periodontitis is associated with several risk factors among which, is tobacco smoking. (3) Throughout the years, studies has recorded delirious effect of smoking on periodontal tissues. However, there were different selected populations and /or different methodologies among these studies. In addition, the precise mechanism by which tobacco influences periodontal destruction and its related alteration still need complementary investigation (4,5,6) . It has been observed that smoking can alter salivary fluid, salivary enzymes. Yet, only a few studies has recorded the effect of tobacco smoking on salivary immunoglobulin (7,8)

The Levels of Salivary IgA and Lactoferrin and Some Salivary Parameters in Waterpipe Smokers and Cigarette Smokers

“…Tobacco showed a controversial effect on salivary IgA levels, some revealed higher s-IgA in smokers in comparison to non-tobacco consumersmay be due to irritation of tobacco to mucosa so IgA defends these membranes from multitudes of soluble antigens (20,21,22) . While others studies showedthat the levels of IgA decrease in smokers when compared with nontobacco users (23) . Another salivary parameter affected by tobacco is Lactoferrin (Lf) whichis an iron-binding protein.…”