Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis

Sur, Mara; Boca, Andreea; Ilieş, Roxana Flavia; Emanuela, Floca; Tătaru, Alexandru; Sur, Lucia

doi:10.3892/etm.2020.9319

Cited by 9 publications

(9 citation statements)

References 21 publications

(18 reference statements)

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“…Hence, AD had a significant impact on their QoL. Similar results were also reported in Romania 2 and Denmark. 3 Furthermore, the impairment of parents’ QoL was highly correlated to the severity of AD in infants aged <5 years.…”

supporting

confidence: 84%

Quality of life in children with atopic dermatitis seen in the department of dermatology at the university hospital, Antananarivo Madagascar

Sendrasoa¹,

Razafimaharo²,

Ramarozatovo³

et al. 2023

JAAD International

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supporting

confidence: 84%

Quality of life in children with atopic dermatitis seen in the department of dermatology at the university hospital, Antananarivo Madagascar

Sendrasoa¹,

Razafimaharo²,

Ramarozatovo³

et al. 2023

JAAD International

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“…Some studies in Colombia, Argentina, and Brazil evaluated the impact of AD on QoL, according to multiple scales (Skindex, Dermatology Life Quality Index, Infants' Dermatitis Quality of Life Index, Dermatitis Family Impact Questionnaire) 67–70 . In line with the global findings, 63 these studies unanimously agree that QoL and disease activity are correlated.…”

Section: Unmet Needs Of Ad In Lamentioning

confidence: 84%

Atopic Dermatitis in Latin America: A Roadmap to Address Data Collection, Knowledge Gaps, and Challenges

et al. 2022

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BackgroundAtopic dermatitis (AD) is a systemic, multifactorial disease that causes significant morbidity and health care burden in Latin America (LA). Data on AD are scarce in LA. Lack of disease registries and non-standardized study methodologies, coupled with region-specific genetic, immunological, and environmental factors, hamper data collection. A panel of LA experts in AD was given a series of relevant questions to address before a conference. Each narrative was discussed and edited through numerous rounds of deliberation until achieving consensus. Identified knowledge gaps in AD research were updated prevalence, adult-disease epidemiology, local phenotypes and endotypes, severe-disease prevalence, specialist distribution, and AD public health policy. Underlying reasons for these gaps include limited funding for AD research, from epidemiology and public policy to clinical and translational studies. Regional heterogeneity requires that complex interactions between race, ethnicity, and environmental factors be further studied. Informed awareness, education, and decision making should be encouraged.

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“…A previous study similarly identified emotional distress and sleep disturbance as the most reported QoL subdomains (after itching/scratching) in pediatric patients with AD aged 0–16 years [ 32 ]. Other studies have reported the highest impact of AD to be on school/holidays, itch, and free time/hobbies (for patients aged 5–9 years) or school/holidays, friendships, and either itch or free time/hobbies (for patients aged 10–16 years) [ 33 , 34 ].…”

Section: Discussionmentioning

confidence: 99%

Similarities and Differences in the Perception of Atopic Dermatitis Burden Between Patients, Caregivers, and Independent Physicians (AD-GAP Survey)

Paller

Weidinger

Capozza

et al. 2023

Dermatol Ther (Heidelb)

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Introduction Atopic dermatitis (AD)—a chronic inflammatory skin disease characterized by intense itching—can have a detrimental impact on quality of life (QoL). We report results of a quantitative assessment of pediatric patient, caregiver, and physician perceptions of AD burden in children and adolescents. Methods Pediatric patients (aged 6–11 [children] or 12–17 [adolescents] years) with moderate-to-severe AD, their caregivers, and independent physicians were recruited in 13 countries. Caregivers and their children/adolescents completed an online survey about the impact of AD on 16 key items of patient QoL. Physicians completed surveys on their patients aged 6–11 and 12–17 years. Best–worst scaling was used to rank the importance of the QoL items. Results Overall, 1447 children/adolescents with moderate-to-severe AD (aged 6–11 years: 701; 12–17 years: 746), 1447 caregivers, and 1092 physicians participated. Patients and caregivers in both age groups ranked disturbed sleep as the most important QoL item, followed by feeling ashamed because of AD. Independent physicians ranked feeling ashamed because of AD as the most important QoL item for both age groups, followed by disturbed sleep for those aged 6–11 years and being singled out for those aged 12–17 years. The relative importance of the 16 QoL items to patients was strongly aligned between patients in both age groups and their caregivers, but somewhat less so between patients and physicians. Between-country differences were more apparent in physician- versus patient-/caregiver-reported results. Conclusion The most burdensome QoL items were impact of AD on sleep and feeling ashamed. Caregivers and physicians correctly identified the QoL items most burdensome to patients. However, patient and caregiver perceptions were generally more closely aligned than patient and physician perceptions. Between-country differences in perceptions (particularly for physicians) were observed, probably due to multifactorial reasons, necessitating further evaluation. Infographic Supplementary Information The online version contains supplementary material available at 10.1007/s13555-022-00850-7.

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Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis

Cited by 9 publications

References 21 publications

Quality of life in children with atopic dermatitis seen in the department of dermatology at the university hospital, Antananarivo Madagascar

Quality of life in children with atopic dermatitis seen in the department of dermatology at the university hospital, Antananarivo Madagascar

Atopic Dermatitis in Latin America: A Roadmap to Address Data Collection, Knowledge Gaps, and Challenges

Similarities and Differences in the Perception of Atopic Dermatitis Burden Between Patients, Caregivers, and Independent Physicians (AD-GAP Survey)

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