Correlation between Proteinuria and Glomerular Filtration Rate in Type 2 Diabetes Mellitus

Rosdiana, Dani; Mukhyarjon, Mukhyarjon; Asputra, Hendra; Hernita, Nisa Faradisa; Makmur, Olivia; Prayogo, Prayogo; Hirfawaty, Hetty

doi:10.15395/mkb.v52n2.1811

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“…There was a lower incidence of albuminuria in the group of patients with controlled HbA1c levels, while a higher incidence of albuminuria in the group of uncontrolled HbA1c levels. Our results are similar to a study showing a higher incidence of albuminuria in the group with HbA1c >7 (15,16). Also were confirmed by another study which stated that there was a significant relationship between HbA1c levels and albuminuria in type 2 DM patients (17,18).…”

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confidence: 92%

HbA1c levels with albuminuria in diabetes mellitus patients

Hidayati¹,

Kanang²,

Razak³

et al. 2021

Gaceta Médica De Caracas

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Introduction: The number of people with diabetes mellitus (DM) worldwide with kidney complications has increased. Glycemic control by assessing HbA1c levels is one factor that influences the occurrence of kidney damage in DM patients. This study aims to determine the relationship between HbA1c levels and the incidence of albuminuria in DM patients. Methods: This study was a cross-sectional analytic observational study with consecutive sampling techniques in DM patients who did not have urinary tract infections and had no history of other kidney diseases, which were then measured for HbA1c levels and protein in the urine. Results: A total of 20 patients (62.5 %) were female, and 12 patients (37.5 %) were male. The average age of the patients was 59.81±4.89 years, and the average length of suffering from DM was 6.21±2.27 years. The average HbA1c level was 8.63±2.15, with an HbA1c level >7 found in 21 patients (65.7 %). In this study, there were 21 patients (65.7 %) with uncontrolled HbA1c levels. In this study, the prevalence of negative albuminuria was 56.2 %, while the prevalence of positive albuminuria was 43.8 %. There was a significant relationship between uncontrolled HbA1c levels and the incidence of albuminuria in DM patients (p=0.03). Conclusion: Uncontrolled HbA1c levels were associated with the incidence of albuminuria in DM patients.

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