Correlation Between Preoperative Magnetic Resonance Imaging and Surgical Margins with Modified Mohs for Dermatofibrosarcoma Protuberans

Abstract

We present the largest series of DFSP cases studied using MRI published to date. In primary cases, MRI has greater sensitivity than palpation for detecting depth of infiltration (67% vs 58%). MRI seems to be useful in primary DFSP in locations other than the head, neck, and upper part of the thorax. MRI is not useful for confirming tumor persistence in extirpated DFSP with positive margins or for studying lateral extension in primary DFSP.

Dermatofibrosarcoma protuberans of the breast: A case report

“…As DFSP metastasizes in 2–5% of cases, extensive evaluations with computed tomography scans and laboratory tests are not usually recommended (5,13). Generally, imaging results for DFSP are nonspecific, but they may aid in defining the diagnosis in an appropriate clinical setting (11–13). …”

Mohs micrographic surgery in dermatofibrosarcoma protuberans allows tumour clearance with smaller margins and greater preservation of healthy tissue compared with conventional surgery: a study of 74 primary cases

“…There is a long‐standing debate on whether DFSP should be treated with conventional surgery (CS) or Mohs micrographic surgery (MMS). While recent studies involving large series of patients with DFSP advocate the use of CS, others report that MMS is associated with lower rates of recurrence . Nevertheless, none of the studies that have directly compared the two treatment modalities has provided conclusive evidence that MMS should be the treatment of choice in DFSP …”

Role of diffusion‐weighted magnetic resonance imaging in the evaluation of scalp dermatofibrosarcoma protuberans

“…Serra‐Guillén et al . compared clinical palpation to MRI in delimiting the invasion depth of DFSP and found a greater sensitivity for MRI in detecting a depth of infiltration in primary cases (67% vs. 58%).…”

“…Several authors already evaluated the use of magnetic resonance imaging (MRI) for DFSP. Most of them use conventional T1‐ and T2‐weighted sequences . We investigated the use of diffusion‐weighted imaging (DWI) in preoperative assessment and postoperative follow‐up.…”