Correlation between pain and MRI findings in TMD patients

Wurm, Matthias C.; Behrends, Tessa K; Wüst, Wolfgang; Wiesmüller, Marco; Wilkerling, André; Neukam, Friedrich Wilhelm; Schlittenbauer, Tilo

doi:10.1016/j.jcms.2017.12.029

Cited by 20 publications

(12 citation statements)

References 31 publications

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“…Most often the temporomandibular joint current MR images are obtained using 1.5-T MRI systems [31][32][33][34][35][36][37][38]. Manoliu et al [38] quantitatively and qualitatively compared MRI images of TMJ using two different protocols at 1.5 T and at 3.0 T. According to the authors, imaging at 3.0 T is recommended because of significantly better quality, visibility and delineation of anatomical structures, including articular disc and masticatory muscles.…”

Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Interdisciplinary Approach to the Temporomandibular Joint Osteoarthritis—Review of the Literature

2020

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Background and objectives: There is an increasing number of patients applying for dental treatment who suffer from temporomandibular joint osteoarthritis (TMJOA). Osteoarthritis may be the cause of the pain in the area of temporomandibular joints, but its course may also be absolutely asymptomatic. The aim of this study was to present an interdisciplinary approach to TMJOA, including current diagnostics and treatment modalities on the basis of the available literature. Materials and Methods: PubMed and Scopus databases were analyzed using the keywords: ((temporomandibular joint AND osteoarthritis) AND imaging) and ((temporomandibular joint AND osteoarthritis) AND treatment). The bibliography was supplemented with books related to the temporomandibular joint. After screening 2450 results, the work was based in total on 98 publications. Results and Conclusions: Osteoarthritis is an inflammatory, age-related, chronic and progressive degenerative joint disease. Magnetic resonance imaging (MRI) and cone-beam computed tomography (CBCT), together with clinical symptoms, play significant roles in TMJOA diagnosis. Current MRI techniques seem to be clinically useful for assessment of bony changes in temporomandibular joint (TMJ) disorders. Treatment of TMJOA requires a complex, interdisciplinary approach. TMJOA treatment includes the cooperation of physiotherapists, rheumatologists, gnathologists, orthodontists and quite often also maxillofacial surgeons and prosthodontists. Sometimes additional pharmacotherapy is indicated. Thorough examination of TMJ function and morphology is necessary at the beginning of any orthodontic or dental treatment. Undiagnosed TMJ dysfunction may cause further problems with the entire masticatory system, including joints, muscles and teeth.

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Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Interdisciplinary Approach to the Temporomandibular Joint Osteoarthritis—Review of the Literature

2020

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“…; Wurm et al. ), which leads to a substantial amount of lost information. Hence, most research focused on the central part of the disc, where the structure is mostly perpendicular to the imaging plane.…”

Section: Discussionmentioning

confidence: 99%

“…; Wurm et al. ). Regardless, MRI continues to be the most promising tool for the detailed, in vivo investigation of disc positioning as well as shape.…”

Section: Introductionmentioning

confidence: 98%

In vivo prediction of temporomandibular joint disc thickness and position changes for different jaw positions

et al. 2019

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Temporomandibular joint disorders (TMD) are common dysfunctions of the masticatory region and are often linked to dislocation or changes of the temporomandibular joint (TMJ) disc. Magnetic resonance imaging (MRI) is the gold standard for TMJ imaging but standard clinical sequences do not deliver a sufficient resolution and contrast for the creation of detailed meshes of the TMJ disc. Additionally, bony structures cannot be captured appropriately using standard MRI sequences due to their low signal intensity. The objective of this study was to enable researchers to create high resolution representations of all structures of the TMJ and consequently investigate morphological as well as positional changes of the masticatory system. To create meshes of the bony structures, a single computed tomography (CT) scan was acquired. In addition, a high-resolution MRI sequence was produced, which is used to collect the thickness and position change of the disc for various static postures using bite blocks. Changes in thickness of the TMJ disc as well as disc translation were measured. The newly developed workflow successfully allows researchers to create high resolution models of all structures of the TMJ for various static positions, enabling the investigation of TMJ disc translation and deformation. Discs were thinnest in the lateral part and moved mainly anteriorly and slightly medially. The procedure offers the most comprehensive picture of disc positioning and thickness changes reported to date. The presented data can be used for the development of a biomechanical computer model of TMJ anatomy and to investigate dynamic and static loads on the components of the system, which could be useful for the prediction of TMD onset.

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“…Given that pain can affect quality of life, and the symptoms can be chronic and difficult to manage, plenty of studies have focused on the mechanisms of pain in TMD patients. In addition to magnetic resonance imaging (MRI), 18 white matter imaging and structural gray matter imaging techniques have provided an innovative comprehension of structural and functional brain alterations in TMD patients to further investigate the neurophysiological mechanisms. 19 These studies provide evidence that the dysfunctions of the peripheral and central nervous system occur in TMD-related pain.…”

Section: Neurobiological Mechanisms Of Tmdmentioning

confidence: 99%

Animal Models of Temporomandibular Disorder

Xiang

Tao

Liao

et al. 2021

JPR

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Temporomandibular disorders (TMD) are a group of diseases in the oral and maxillofacial region that can manifest as acute or chronic persistent pain, affecting millions of people worldwide. Although hundreds of studies have explored mechanisms and treatments underlying TMD, multiple pathogenic factors and diverse clinical manifestations make it still poorly managed. Appropriate animal models are helpful to study the pathogenesis of TMD and explore effective treatment measures. At present, due to the high cost of obtaining large animals, rodents and rabbits are often used to prepare TMD animal models. Over the past decade, various animal models have been intensively developed to understand neurobiological and molecular mechanisms of TMD, and seek effective treatments. Although these models cannot carry out all clinical features, they are valuable in revealing the mechanisms of TMD and creating curative access. Currently, there are multitudinous animal models of TMD research. They can be constructed in different means and summarized into four ways according to the various causes and symptoms, including chemical induction (intra-articular injection of ovalbumin, collagenase, formalin, vascular endothelial growth factor, intramuscular injection of complete Freund's adjuvant, etc.), mechanical stress stimulation (passive mouth opening, change of chewing load), surgical operation (partial disc resection, joint disc perforation) and psychological stress induction. Here, we summarize and discuss different approaches of animal models for determining neurophysiological and mechanical mechanisms of TMD and assess their advantages and limitations, respectively.

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Correlation between pain and MRI findings in TMD patients

Cited by 20 publications

References 31 publications

Interdisciplinary Approach to the Temporomandibular Joint Osteoarthritis—Review of the Literature

Interdisciplinary Approach to the Temporomandibular Joint Osteoarthritis—Review of the Literature

In vivo prediction of temporomandibular joint disc thickness and position changes for different jaw positions

Animal Models of Temporomandibular Disorder

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