2012
DOI: 10.1007/s00417-012-2156-8
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Correlation between multifocal pattern electroretinography and Fourier-domain OCT in eyes with temporal hemianopia from chiasmal compression

Abstract: mfPERG amplitudes and OCT measurements are significantly correlated in patients with chiasmal compression. Both technologies can quantify neuronal loss and, if used in combination, may help clarify structure-function relationships in this patient population.

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Cited by 19 publications
(4 citation statements)
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“…The mfVEP has also been studied in compressive anterior pathway lesions and tends to show similar changes to behavioural perimetric findings [ 123 126 ], but are of debatable clinical use over existing techniques due to their demanding technical requirements. Interestingly, the mfPERG has been demonstrated to show good correlation between amplitude and degree of VF defect in chiasmatic lesions [ 49 , 50 ].
Fig.
…”
Section: Compressive Infiltrative Toxic and Nutritional Optic Neuropathiesmentioning
confidence: 99%
“…The mfVEP has also been studied in compressive anterior pathway lesions and tends to show similar changes to behavioural perimetric findings [ 123 126 ], but are of debatable clinical use over existing techniques due to their demanding technical requirements. Interestingly, the mfPERG has been demonstrated to show good correlation between amplitude and degree of VF defect in chiasmatic lesions [ 49 , 50 ].
Fig.
…”
Section: Compressive Infiltrative Toxic and Nutritional Optic Neuropathiesmentioning
confidence: 99%
“…The technique has already been shown to correlate well with OCT findings for VF defects and RGC defects, such as in hemianopia due to chiasmal compression (89) . However, in three major studies involving glaucoma patients, mfPERG did not reflect localized ganglion cell loss (90)(91)(92) .…”
Section: Abnormalities In Mfpergmentioning
confidence: 85%
“…Loss of RGC was observed on the macular scans as reduced total retinal thickness on the older generation TD-OCT devices and reduced mGCIPL thickness on the current FD-OCT scans. 24,26,29,30,36,40,41 Thinning of mGCIPL and retinal thickness shows vertical asymmetry with more pronounced loss involving the nasal hemimacula which reflects damage to the decussating nasal hemiretinal RGC axons at the chiasm. 30,36 Segmentation of macular structures was shown to be better at detecting chiasmal compression compared with total retinal thickness.…”
Section: Oct As a Diagnostic Tool For Chiasmal And Optic Nerve Compre...mentioning
confidence: 99%