Correlation Between Monocytic Chemotactic Protein-1 (Mcp-1) and the Severity of Covid-19 Infection.

Abstract

Background:The ongoing pandemic of coronavirus disease 2019 poses several challenges to clinicians. Serum chemokine levels such as MCP-1and IL-6 are elevated in patients with COVID-19, and they are even higher in those who required intensivecare unit (ICU) admission, suggesting a relationship between these chemokines and both lung damage and disease severity. Aim of the study:To evaluate the level of monocytic chemotactic protein-1 (MCP-1) in mild, severe and post COVID-19 patients to explore the correlation between (MCP-1) and the severity of the disease. The findings of this study will add to our understanding the role of MCP-1 in diagnosis of COVID-19 patients and the relation between MCP-1 level and the severity of the disease, providing potential diagnostic, prognostic and even therapeutic strategies for COVID-19 patients using MCP-1 as a marker.