“…Four studies found a statistically significant difference between the proportion of MS patients who had anti-HHV-6 serum IgG antibodies compared with controls and were classified as high quality (A). 14, 15,17,28 Four studies were classified as A quality but did not reach statistical significance. 13,16,18,19 Of those 4 studies, 2 considered mean antibody titers rather than an arbitrary positive titer.…”