Correlation between Endodontic Infection and Periodontal Disease and Their Association with Chronic Sinusitis: A Clinical-tomographic Study

Lima, Carolina Oliveira de; Devito, Karina Lopes; Vasconcelos, Letícia Raquel Baraky; Prado, Maíra do; Campos, Celso Neiva

doi:10.1016/j.joen.2017.08.014

Cited by 28 publications

(36 citation statements)

References 27 publications

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“…Five were carried out in Brazil, four in Switzerland and the rest in other countries. Of the total studies, 16 evaluated TSM, two measured TSM and OMS (8,19), and four assessed only OMS (20)(21)(22)(23). In addition to TSM or OMS, a number of studies evaluated other sinus disorders such as MRC (8,21,24,25) and opacities (9).…”

Section: Resultsmentioning

confidence: 99%

“…Prevalence of odontogenic maxillary sinusitis and periapical lesions: Of the articles included in our review, 6 examined OMS in relation to dental disease (8,(19)(20)(21)(22)38), though only Kasikcioglu et al found an association between maxillary sinusitis and PALs, with a significant OR of 2.03 (95%CI: 1.31-3.13). This relationship proved significant in relation to the posterior teeth, particularly the first and second molars (22).…”

Section: Resultsmentioning

confidence: 99%

“…Three studies reported a significant association between proximity of the diseased roots to the sinus and the prevalence of sinus disease (4,8,34). Oliveira de Lima et al (20) found that the shorter the distance separating roots with endodontic infection from the maxillary sinus, the greater the risk of chronic maxillary sinusitis. In contrast, a 2.5-fold decrease in risk was observed as the mentioned distance increased (p<0.05).…”

Section: Resultsmentioning

confidence: 99%

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Association between maxillary sinus pathology and odontogenic lesions in patients evaluated by cone beam computed tomography. A systematic review and meta-analysis

Peñarrocha-Oltra¹,

Soto-Peñaloza²,

Bagán-Debón³

et al. 2020

Med Oral

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Background: A study is made of the association between maxillary sinus pathology and odontogenic lesions in patients evaluated with cone beam computed tomography. Material and Methods: A literature search was made in five databases and OpenGrey. Methodological assessment was carried out using the Newcastle-Ottawa tool for observational studies. The random-effects model was used for the meta-analysis. Results: Twenty-one studies were included in the qualitative review and 6 in the meta-analysis. Most presented moderate or low risk of bias. The periodontal disease showed to be associated with the thickening of the sinus membrane (TSM). Mucous retention cysts and opacities were reported in few studies. The presence of periapical lesions (PALs) was significantly associated to TSM (OR=2.43 (95%CI:1.71-3.46); I2=34.5%) and to odontogenic maxillary sinusitis (OMS)(OR=1.77 (95%CI: 1.20-2.61); I2=35.5%). Conclusions: The presence of PALs increases the probability of TSM and OMS up to 2.4-fold and 1.7-fold respectively. The risk differences suggests that about 58 and 37 of out every 100 maxillary sinuses having antral teeth with PALs are associated with an increased risk TSM and OMS respectively. The meta-evidence obtained in this study was of moderate certainty, and although the magnitude of the observed associations may vary, their direction in favor sinus disorders appearance, would not change as a result.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Association between maxillary sinus pathology and odontogenic lesions in patients evaluated by cone beam computed tomography. A systematic review and meta-analysis

Peñarrocha-Oltra¹,

Soto-Peñaloza²,

Bagán-Debón³

et al. 2020

Med Oral

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“…The most important confounding variable is periodontal disease which has been shown to be significantly associated with diabetes (Nascimento et al 2018, Madianos & Koromantzos 2018 and with endodontic disease (de Lima et al 2017). Other potential confounders include patient-related factors such as age, gender, genomic polymorphisms and teeth with/without a permanent restoration.…”

Section: Other Potential Confoundersmentioning

confidence: 99%

Association between diabetes and the outcome of root canal treatment in adults: an umbrella review

et al. 2019

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Background Diabetes mellitus is the most common metabolic disorder amongst dental patients. The association between the diabetes and the outcome of root canal treatment is unclear. Aim To conduct an umbrella review to determine whether there is an association between diabetes and the outcome of root canal treatment. Data source The protocol of the review was developed and registered in the PROSPERO database (CRD42019141684). Four electronic databases (PubMed, EBSCHOhost, Cochrane and Scopus databases) were used to perform a literature search until July 2019. Study eligibility criteria, participants and interventions Systematic reviews with or without meta‐analyses published in English assessing any outcomes of root canal treatment comparing diabetic and nondiabetic patients were included. Two reviewers were involved independently in study selection, data extraction and appraising the reviews that were included. Disagreements were resolved with the help of a third reviewer. Study appraisal and synthesis methods The quality of the reviews was assessed using the AMSTAR tool (A measurement tool to assess systematic reviews), with 11 items. Each AMSTAR item was given a score of 1 if the criterion was met, or 0 if the criterion was not met or the information was unclear. Results Four systematic reviews were included. The AMSTAR score for the reviews ranged from 5 to 7, out of a maximum score of 11, and all the systematic reviews were classified as ‘medium’ quality. Limitations Only two systematic reviews included a meta‐analysis. Only systematic reviews published in English were included. Conclusions and implications of key findings Diabetes mellitus is associated with the outcome of root canal treatment and can be considered as a preoperative prognostic factor.

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“…CMOS is an inflammation of the maxillary sinus caused by dental infection. Patients with chronic periodontitis have an increased risk of developing maxillary sinusitis caused by intra-antral foreign bodies or by oroantral fistulas after tooth extraction [1,2]. According to the literature in the field, the incidence of this disease in the adult population is 10-12%, but according to the latest studies, the incidence increased to 41% [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Effect of platelet-rich plasma on chronic odontogenic maxillary sinusitis: a pilot study

Miricescu¹,

Totan²,

Rusu³

et al. 2019

EDUJ

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Introduction: Chronic odontogenic maxillary sinusitis (CMOS) is a frequent inflammatory process pertaining to the oro-maxilo-facial pathology. Platelet-rich plasma (PRP) is a natural source of growth factors, which have the potential to stimulate and accelerate the wound healing process. The aim of this study is to observe the effects of the PRP growth factors in patients with CMOS. Methodology: Inflammatory oral mucosa was collected from five patients diagnosed with CMOS, and it was incubated with 2 mL PRP for 7 days. PRP was obtained from venous blood collection from each patient. The control samples were represented by inflammatory sinus mucosa without adding PRP. The following biomarkers were measured using cell lysate: insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF-1R), glycogen synthase kinase 3 beta (GSK3β), glycogen synthase kinase 3 alfa (GSK3α) performed by Multiplex technology. Results: The results revealed statistically increased levels for all four parameters in patients with CMOS versus controls (p < 0.05). Growth factors from PRP bind to receptors with tyrosine kinase activity, cellular event being correlated with cell proliferation. The radiological control of patients 10 months after PRP administration revealed a decrease in the thickness of the sinus lining up to 3 times. Conclusions: The growth factors released from platelets should be regarded as a positive effect source in the case of patients diagnosed with CMOS. These growth factors should activate the oligopotente stem cells which will finally lead to sinus mucosa regeneration. Future studies are needed to understand the molecular mechanisms that occur at the sinus level.

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Correlation between Endodontic Infection and Periodontal Disease and Their Association with Chronic Sinusitis: A Clinical-tomographic Study

Cited by 28 publications

References 27 publications

Association between maxillary sinus pathology and odontogenic lesions in patients evaluated by cone beam computed tomography. A systematic review and meta-analysis

Association between maxillary sinus pathology and odontogenic lesions in patients evaluated by cone beam computed tomography. A systematic review and meta-analysis

Association between diabetes and the outcome of root canal treatment in adults: an umbrella review

Effect of platelet-rich plasma on chronic odontogenic maxillary sinusitis: a pilot study

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