Correlation between ellipsoid zone thickness and the presence of subretinal drusenoid deposits in age-related macular degeneration
Raymond Matthew Bellis,
Yang Fei,
Brandon Le
et al.
Abstract:PurposeSubretinal drusenoid deposits (SDDs) in age-related macular degeneration (AMD) are associated with systemic vascular diseases that compromise ocular perfusion. We demonstrate that SDDs are associated with decreased ellipsoid zone (EZ) thickness, further evidence of hypoxic damage.MethodsPost hoc analysis of a cross-sectional study. 165 AMD subjects (aged 51–100; 61% women). Spectral-domain optical coherence tomography was obtained in both eyes. Masked readers assigned subjects to three groups: drusen on… Show more
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