Correlation between DKK-1 Level and Bone Density Status in Children on Maintenance Haemodialysis
Manal Abd El-Salam,
Marwa Mohamed Anwar,
Rasha Mahmoud Gouda
et al.
Abstract:Background: Renal osteodystrophy (ROD) is a bone disorder resulting from chronic kidney disease (CKD) and related metabolic diseases. Dickkopf-related protein-1 (DKK-1) is critical in regulating bone biology. This study aimed to evaluate the serum DKK-1 level as a bone marker in children with CKD who undergo regular hemodialysis (HD). Subjects and Methods: This case-control study involved 40 children with CKD on HD and 40 healthy children as controls. The study measured serum DKK-1 levels and performed a dual-… Show more
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