Correlation between central corneal thickness and myopia

Flores, Víctor Hugo Portilla; Shapira, Yinon; Graffi, Shmuel; Levartovsky, Shmuel; Sela, Tzahi; Munzer, Gur; Kaiserman, Igor

doi:10.1007/s10792-017-0766-1

Cited by 15 publications

(14 citation statements)

References 25 publications

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“…According to the study of Hashman N, they showed that males had significantly smaller skin corneas than females [30]. Also CCT did not show any gender difference, according to M. Micheal [20].…”

Section: Discussionmentioning

confidence: 94%

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Determination of Central Corneal Thickness in Patients with Refractive Anomalies and Emmetropy

Ismaili¹,

Kaçaniku²,

Spahiu³

et al. 2019

OJOph

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Aim: The purpose of this study was to compare measurements of CCT in emmetropia and patient with refractive anomalies. Methods: We represent a retrospective research which was conducted at the University Clinical Center of Kosovo (UCCK). In this study were included 80 patients, divided into two groups: test and a control group. Mean age was (M = 25.90, DS = 7.16), men (N = 41% or 51.3%) and women (N = 39% or 48%). Results: Results show that there were no differences in the CCT, Hyperopic (M = 545.21 DS = 52.24), Myopic (M = 547.90 DS = 47.93) and Emmetropic (M = 550.75 DS = 41.29). After measuring of the longitudinal axis and analyzing the data by means of Anova test, it appeared to be a significant difference between the analyzed groups, Hyperopic (M = 21.99, DS = 1.27), Myopics (M = 23.21, DS = 1.24), Emmetropic (M = 22.36, DS = 0.81). Results also revealed that there is correlation between the CCT and IOP, where increase CCT decreases IOP and vice versa (r = −0.26, p = 0.01). Conclusion: The results have shown that CCT is thinner in myopic but does not show correlation with hypermetropic and emmetropic. While during the measurement of central corneal thickness and eye tension it is found that there is a negative correlation between them. Keratometry has a negative correlation with CCT. While there was no correlation between CCT and age. Given the role of CCT in interpreting IOP values, it is recommended to perform a systematic CCT measurement in routine clinical practice, which would assist in the diagnosis of ocular hypertension.

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Section: Discussionmentioning

confidence: 94%

“…Bradfield reported that for every degree of increased myopic refractive error CCT is 1 µm thinner than average [19]. According to Michael Mimouni, CCT is associated with the degree of myopia in adults who will undergo refractive surgery [20].…”

Section: Discussionmentioning

confidence: 99%

Determination of Central Corneal Thickness in Patients with Refractive Anomalies and Emmetropy

Ismaili¹,

Kaçaniku²,

Spahiu³

et al. 2019

OJOph

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“…Srivannaboon 24 reported a positive correlation between myopia and central corneal thickness (CCT) and high myopes (>6 D) have been reported to have a greater CCT than moderate and mild myopes. 25 Others, however, found a negative correlation 26 or no correlation. [27][28][29] It seems as though the studies with very large cohorts (as opposed to those with smaller cohorts) identified small magnitudes of correlation between refractive error and corneal thickness which, again, are of unclear clinical significance.…”

Section: Discussionmentioning

confidence: 99%

Correlation between refractive state, corneal thickness, and keratometry in ametropic patients

Rosenblatt

Sela

Munzer

et al. 2019

European Journal of Ophthalmology

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Purpose: To analyze the correlation between age, gender, refractive error, keratometry, and corneal thickness in a large group of subjects. Methods: This study is a retrospective analysis of patients who underwent refractive surgery between January 2000 and February 2015 at Care Vision Refractive Clinic, Tel Aviv, Israel. Patient demographics, subjective refraction, pachymetry, and average keratometry were collected. Results: Overall, 51,113 eyes of patients averaging 28.8 ± 9.3 years of which 53.9% were males were included. Average keratometry, spherical equivalent and cylindrical error differed significantly between male and female subjects (p < 0.001), while pachymetry did not (p = 0.332). In myopic eyes, correlations between age, pachymetry, average keratometry, spherical equivalent, and cylindrical error were all statistically significant except for the correlation between age and either pachymetry (p = 0.462) or spherical equivalent (p = 0.016). All correlations found were negligible or small (|r|= 0.003 to 0.141). In hyperopic eyes, correlations between age, pachymetry, average keratometry, spherical equivalent, and cylindrical error were all statistically significant except for the correlation between average keratometry and either pachymetry or cylindrical error (p = 0.344 or p = 0.274, respectively). All correlations found were negligible or small, except for a moderate correlation found between age and cylindrical error (r = 0.365). Conclusion: Refractive state, pachymetry, and keratometry of refractive surgery candidates are mostly weakly correlated.

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“…Increased care on the corneal thickness has brought about its description in a considerable number of studies from different regions and countries [23][24][25][26][27][28]. For the contrasts in ethnicity, geography, and other environmental variables, there is a wide-extending variety within these records; in this way, reference values of the corneal thickness-related parameters should not be utilized imprecisely and should be sensitive to variations within each population.…”

Section: Discussionmentioning

confidence: 99%

Reference values of the central corneal thickness with different refractive errors for the adult Egyptian population

Gab-Alla¹

2020

Preprint

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Abstract Background: To generate reference values of the central corneal thickness (CCT) with different refractive errors for the adult Egyptian population. Methods: A retrospective, observational, and cross-sectional study of 2200 eyes in 1166 subjects scheduled for LASIK, who came to private refractive eye center, Ismailia, Egypt. The study period was from January 2018 to January 2020. The subjects were divided into a broad range of myopia with spherical equivalent (SE) <-0.5D and hyperopia SE> +0.5D. Then, the myopic eyes divided into low (SE>-3.0D), moderate (SE-3.0D to >-6.0D), and high (SE<-6.0D). Similarly, the hyperopic eyes were divided into low (SE<+3.0 D) and moderate (SE+3.0D to <+6.0D) and high >+6.0D. The refractive error was measured by an auto-refractometer (Topcon, Tokyo Optical Co., Ltd., Japan), and CCT was measured using Sirius (CSO, Florence, Italy). Results: The data of 1100 myopic eyes in 556 subjects (30.5% males and 69.5% females) and 1100 hyperopic eyes in 610 subjects (33.6% males and 66.4% females). The mean+SD of CCT for the total myopic subjects was 531.98+32.92μm, range (406 to 636μm). The mean+SD of SE was -4.1±2.5D, range (-0.5 to -12.0D). The mean+SD of CCT for the total hyperopic subjects was 529±38.8μm, range (448 to 619 μm). The mean+SD of SE was +3.65+1.97D, range (+0.5 to +8.5D).Conclusion: In this study, the mean of CCT of the Egyptian population was 531.9 μm for myopic and 529μm for hyperopic subjects respectively. The myopic and hyperopic subjects show a reduction in CCT with age. Females have a thinner cornea than males, 23.6% of the myopic eyes, and 16.5% of the hyperopic eyes have CCT less than 500μm.

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Correlation between central corneal thickness and myopia

Abstract: Central corneal thickness is correlated with the degree of myopia among adults undergoing refractive surgery.

Cited by 15 publications

References 25 publications

Determination of Central Corneal Thickness in Patients with Refractive Anomalies and Emmetropy

Determination of Central Corneal Thickness in Patients with Refractive Anomalies and Emmetropy

Correlation between refractive state, corneal thickness, and keratometry in ametropic patients

Reference values of the central corneal thickness with different refractive errors for the adult Egyptian population

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