Correlation between B-Type Natriuretic Peptide and N-Terminal pro-B-Type Natriuretic Peptide in a Large Japanese Population at Risk of Stage A Heart Failure

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“…NT-proBNP was converted to BNP according to the following formula: log(BNP) = -0.127 + 0.815 × log(NT-proBNP). 10 …”

Section: Methodsmentioning

confidence: 99%

Intracardiac conduction time as a predictor of cardiac resynchronization therapy response: Results of the BIO|SELECT pilot study

et al. 2021

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Prognostic effects of cardiac rehabilitation in heart failure patients classified according to physical frailty: A propensity score–matched analysis of a nationwide prospective cohort study

Adachi¹,

Iritani²,

Kamiya³

et al. 2023

International Journal of Cardiology Cardiovascular Risk and Pre

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Evaluation of the A ₂ B Score for Prediction of Survival in Patients With Heart Failure in a Nationwide Cohort in Japan

Kyodo,

Nakada,

Nogi

et al. 2024

JAHA

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Background Although a tool for sharing patient prognosis among all medical staff is desirable in heart failure (HF) cases, only a few simple HF prognostic scores are available. We previously presented the A 2 B score, a simple user‐friendly HF risk score, and validated it in a small single‐center cohort. In the present study, we validated it in a larger nationwide cohort. Methods and Results We examined the 2‐year mortality in relation to the A 2 B scores in 3483 patients from a Japanese nationwide cohort and attempted to stratify their prognoses according to the scores. The A 2 B score was determined by assigning points for age, anemia, and brain natriuretic peptide (BNP) level at discharge: age (<65 years, 0; 65–74 years, 1; ≥75 years, 2), anemia (hemoglobin ≥12 g/dL, 0; 10–11.9 g/dL, 1; <10 g/dL, 2), and BNP (<200 pg/mL, 0; 200–499 pg/mL, 1; ≥500 pg/mL, 2). Hemoglobin and BNP levels were applied to the data at discharge. The 2‐year survival rates for A 2 B scores 1, 2, 3, 4, 5, and 6 were 94.1%, 83.2%, 74.1%, 63.5%, 51.6%, and 41.5%, respectively; the mortality rate increased by ≈10% for each point increase (c‐index, 0.702). The A 2 B score was applicable in HF cases with reduced or preserved ejection fraction and remained useful when BNP was substituted with N‐terminal proBNP (c‐index, 0.749, 0.676, and 0.682, respectively). Conclusions The A 2 B score showed a good prognostic value for HF in a large population even when BNP was replaced with N‐terminal proBNP.

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Correlation between B-Type Natriuretic Peptide and N-Terminal pro-B-Type Natriuretic Peptide in a Large Japanese Population at Risk of Stage A Heart Failure

Cited by 4 publications

References 21 publications

Intracardiac conduction time as a predictor of cardiac resynchronization therapy response: Results of the BIO|SELECT pilot study

Intracardiac conduction time as a predictor of cardiac resynchronization therapy response: Results of the BIO|SELECT pilot study

Prognostic effects of cardiac rehabilitation in heart failure patients classified according to physical frailty: A propensity score–matched analysis of a nationwide prospective cohort study

Evaluation of the A ₂ B Score for Prediction of Survival in Patients With Heart Failure in a Nationwide Cohort in Japan

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Correlation between B-Type Natriuretic Peptide and N-Terminal pro-B-Type Natriuretic Peptide in a Large Japanese Population at Risk of Stage A Heart Failure

Cited by 4 publications

References 21 publications

Intracardiac conduction time as a predictor of cardiac resynchronization therapy response: Results of the BIO|SELECT pilot study

Intracardiac conduction time as a predictor of cardiac resynchronization therapy response: Results of the BIO|SELECT pilot study

Prognostic effects of cardiac rehabilitation in heart failure patients classified according to physical frailty: A propensity score–matched analysis of a nationwide prospective cohort study

Evaluation of the A 2 B Score for Prediction of Survival in Patients With Heart Failure in a Nationwide Cohort in Japan

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Product

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Evaluation of the A ₂ B Score for Prediction of Survival in Patients With Heart Failure in a Nationwide Cohort in Japan