Correlation between aflatoxin M1 content of breast milk, dietary exposure to aflatoxin B1 and socioeconomic status of lactating mothers in Ogun State, Nigeria

Adejumo, Oloyede; Atanda, Olusegun; Raiola, Assunta; Somorin, Yinka; Bandyopadhyay, Ranajit; Ritieni, Alberto

doi:10.1016/j.fct.2013.02.027

Cited by 94 publications

(64 citation statements)

References 19 publications

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“…Also, rural populations suffer poverty more frequently than urban populations in Uganda (Mukwaya et al 2012). The association of AF exposure with poverty has been well proven (Shuaib et al 2012;Adejumo et al 2013).…”

Section: Round (Year)mentioning

confidence: 99%

Longitudinal evaluation of aflatoxin exposure in two cohorts in south-western Uganda

Kang

Nkurunziza

Muwanika

et al. 2015

Food Additives & Contaminants: Part A

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akes every effort t o ensure t he accuracy of all t he inform at ion ( t he " Cont ent " ) cont ained in t he publicat ions on our plat form . However, Taylor & Francis, our agent s, and our licensors m ake no represent at ions or warrant ies what soever as t o t he accuracy, com plet eness, or suit abilit y for any purpose of t he Cont ent . Any opinions and views expressed in t his publicat ion are t he opinions and views of t he aut hors, and are not t he views of or endorsed by Taylor & Francis. The accuracy of t he Cont ent should not be relied upon and should be independent ly verified wit h prim ary sources of inform at ion. Taylor and Francis shall not be liable for any losses, act ions, claim s, proceedings, dem ands, cost s, expenses, dam ages, and ot her liabilit ies what soever or howsoever caused arising direct ly or indirect ly in connect ion wit h, in relat ion t o or arising out of t he use of t he Cont ent . This art icle m ay be used for research, t eaching, and privat e st udy purposes. Any subst ant ial or syst em at ic reproduct ion, redist ribut ion, reselling, loan, sub-licensing, syst em at ic supply, or dist ribut ion in any form t o anyone is expressly forbidden. Term s & Condit ions of access and use can be found at ht t p: / / www.t andfonline.com / page/ t erm s-and-condit ions Aflatoxins (AF) are a group of mycotoxins. AF exposure causes acute and chronic adverse health effects such as aflatoxicosis and hepatocellular carcinoma in human populations, especially in the developing world. In this study, AF exposure was evaluated using archived serum samples from human immunodeficiency virus (HIV)-seronegative participants from two cohort studies in south-western Uganda. AFB 1 -lysine (AFB-Lys) adduct levels were determined via HPLC fluorescence in a total of 713 serum samples from the General Population Cohort (GPC), covering eight time periods between 1989 and 2010. Overall, 90% (642/713) of the samples were positive for AFB-Lys and the median level was 1.58 pg mg −1 albumin (range = 0.40-168 pg mg −1 albumin). AFB-Lys adduct levels were also measured in a total of 374 serum samples from the Rakai Community Cohort Study (RCCS), across four time periods between 1999 and 2003. The averaged detection rate was 92.5% (346/374) and the median level was 1.18 pg mg −1 albumin (range = 0.40-122.5 pg mg −1 albumin). In the GPC study there were no statistically significant differences between demographic parameters, such as age, sex and level of education, and levels of serum AFB-Lys adduct. In the RCCS study, longitudinal analysis using generalised estimating equations revealed significant differences between the adduct levels and residential areas (p = 0.05) and occupations (p = 0.02). This study indicates that AF exposure in people in two populations in south-western Uganda is persistent and has not significantly changed over time. Data from one study, but not the other, indicated that agriculture workers and rural area residents had more AF exposure than those non-agricultural workers and non...

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Section: Round (Year)mentioning

confidence: 99%

Longitudinal evaluation of aflatoxin exposure in two cohorts in south-western Uganda

Kang

Nkurunziza

Muwanika

et al. 2015

Food Additives & Contaminants: Part A

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show abstract

“…Aflatoxins have been found in the urine of liver disease patients in Zaria, in Blood in Southern Nigeria, in organs of children who died of kwashiorkor in Western Nigeria, and in human semen in Benin city (Onyemelukwe 1992, Oluyide 1993, Adegoke et al 1996and Oluwafemi 2005. Similarly Aflatoxin M1 has been found in breast milk and in the blood of umbilical cord of babies in the country (WHO 1997 andAdejumo et al 2012). Doctors at the National hospital Abuja have reported post mortem examination link between the cause of death from liver cancer to Aflatoxin (Paul Jibrin -personal communication).…”

Section: Human Mycotoxicosesmentioning

confidence: 92%

Fungal and Mycotoxin Contamination of Nigerian Foods and Feeds

Atanda¹,

Makun²,

Ogara³

et al. 2013

Mycotoxin and Food Safety in Developing Countries

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“…Children can be exposed to aflatoxins during pregnancy as the toxins pass from mother to fetus through the placental cord (Wild et al 1991). This exposure may continue during breastfeeding (Polychronaki et al 2006(Polychronaki et al , 2007Adejumo et al 2013;Magoha et al 2014b) and extend through the first 1,000 days of life during the introduction of complementary weaning foods (Gong et al 2003;Kimanya et al 2014). Individuals may also be exposed at any time of life through consumption of contaminated foods.…”

Section: Nutrition and Health Implicationsmentioning

confidence: 99%

Achieving a nutrition revolution for Africa: The road to healthier diets and optimal nutrition

Ayalew¹,

Hoffmann²,

Lindahl³

et al. 2016

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Focusing the 2015 Annual Trends and Outlook Report (ATOR) on nutrition will contribute to a broader understanding of the critical role of nutrition in achieving international, continental, and national economic growth targets through agriculture, food security, and nutrition. This report presents information and analysis in support of evidence-based policy making that should inform the second generation of CAADP national investment plans now being developed. This is an important moment for shaping the region’s future and ensuring that the much-needed agriculture-led growth and development agenda can simultaneously deliver on improving nutrition, saving lives, improving productivity and health, and curbing nutrition-related diseases and the associated public health expenditures. These investment plans should address not only the usual elements of undernutrition but also widespread micronutrient deficiencies (termed “hidden hunger”) and the growing problem of overweight and obesity that is associated with economic growth.1 introduction 2 The African union policy environment toward enabling action for nutrition in Africa 3 Africa’s progress toward meeting current nutrition targets 4 Economic development and nutrition transition in Ghana: taking stock of food consumption patterns and trends 5 Making African agriculture and food systems work for nutrition: what has been done, and what needs to be done? 6 Lessons learned from the evaluation of Helen Keller International’s enhanced homestead food production program 7 The role of biofortification as part of more diverse diets in Africa: progress, challenges, and opportunities 8 The role of mycotoxin contamination in nutrition: the aflatoxin story 9 The challenges, opportunities, and lessons learned in evidence-informed decision making in Africa 10 Evaluating nutrition-sensitive programs: challenges, methods, and opportunities 11 Supporting multisectoral action: capacity and nutrition leadership challenges facing Africa 12 Tracking key CAADP indicators and implementation processes 13 Summary and policy recommendations: toward a nutrition revolution for AfricaReportPRIFPRI1; ReSAKSS; HarvestPlus; B Promoting healthy food systemsDSGD; WCAO; ESAO; HarvestPlus; PHND; A4NH; MTIDCGIAR Research Program on Agriculture for Nutrition and Health (A4NH

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Correlation between aflatoxin M1 content of breast milk, dietary exposure to aflatoxin B1 and socioeconomic status of lactating mothers in Ogun State, Nigeria

Cited by 94 publications

References 19 publications

Longitudinal evaluation of aflatoxin exposure in two cohorts in south-western Uganda

Longitudinal evaluation of aflatoxin exposure in two cohorts in south-western Uganda

Fungal and Mycotoxin Contamination of Nigerian Foods and Feeds

Achieving a nutrition revolution for Africa: The road to healthier diets and optimal nutrition

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