Correlation between acid–base parameters measured in arterial blood and venous blood sampled peripherally, from vena cavae superior, and from the pulmonary artery

Toftegaard, Marianne; Rees, Stephen Edward; Andreassen, Steen

doi:10.1097/mej.0b013e3282e6f5c5

Cited by 44 publications

(55 citation statements)

References 13 publications

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“…Recently, studies have shown that values of acidbase status measured in peripheral venous blood correlate well with those measured in arterial blood, at least for values of pH, bicarbonate and carbon dioxide tension (PCO 2 ) [4][5][6]. Large numbers of peripheral venous samples are taken easily and safely in medical departments, therefore implying a role for peripheral venous blood in the monitoring of acid-base status.…”

mentioning

confidence: 99%

Converting venous acid-base and oxygen status to arterial in patients with lung disease

Rees¹,

Hansen²,

Toftegaard³

et al. 2009

European Respiratory Journal

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The aim of the present study was to evaluate a method for calculating arterial values of pH, carbon dioxide tension (PCO 2 ) and oxygen tension (PO 2 ) from peripheral venous values.In total, 40 patients were studied. Arterial and peripheral venous blood were sampled at a department of respiratory diseases. Arterial values were calculated from venous, and measured and calculated values of arterial pH, PCO 2 and PO 2 were compared.Measured and calculated values of pH and PCO 2 correlated well, with the difference between them having a very small bias and standard deviation (pH -0.001¡0.013, PCO 2 -0.09¡0.28 kPa) within those considered acceptable for laboratory equipment and clinical practice. All but four patients had peripheral oxygen saturation (Sp,O 2 ) f96%, and for these measured and calculated PO 2 correlated well, with a difference such that the bias and standard deviation suggested that calculated PO 2 may be clinically useful (PO 2 0.11¡0.53 kPa).The present study evaluates a method for calculating arterial pH, carbon dioxide tension and oxygen tension from venous blood. It has been shown that arterial pH and carbon dioxide tension can be calculated precisely, and that oxygen tension can be calculated with reasonable precision in the vast majority of patients. This method might be useful in reducing the need for painful arterial punctures.

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mentioning

confidence: 99%

Converting venous acid-base and oxygen status to arterial in patients with lung disease

Rees¹,

Hansen²,

Toftegaard³

et al. 2009

European Respiratory Journal

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show abstract

“…• les études citées dans ces articles sont souvent monocentriques, l'échantillon de patients réellement malades (hémo-dynamiquement instables, détresse respiratoire…) faible, et les inclusions non consécutives [6,11,13,18,[22][23][24]27] ;…”

Section: Limitations Des éTudes Consacrées Aux Gaz Sanguins Veineuxunclassified

“…Med. Urgence (2011) 1:103-111 105cliniques réalisées aux urgences ont montré que la limite de précision de cette faible différence de -0,03 point s'étendait de -0,1 à +0,04 [6,11,13,18,[21][22][23]. Ces études ont comparé pH veineux et artériel au cours de pathologies variées vues en médecine d'urgence.…”

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Faut-il encore réaliser des gazométries artérielles au service des urgences ?

Radermecker

Thys

Verschuren

2011

Ann. Fr. Med. Urgence

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Le recours à la gazométrie artérielle constitue jusqu'à présent un acte quotidien du médecin urgentiste, tant à visée d'aide au diagnostic, au pronostic et à la décision thé-rapeutique pour son patient. Cependant, il s'agit d'une procédure douloureuse et invasive exposant le patient ainsi que le soignant à un risque faible mais réel de complications. Depuis quelques années, divers auteurs se sont intéressés aux techniques alternatives permettant de diminuer le recours à la gazométrie artérielle : l'analyse des gaz du sang veineux et la saturométrie par oxymétrie pulsée. L'objectif de cet article consiste à revoir les indications de l'analyse des gaz du sang et à préciser les circonstances dans lesquelles la gazométrie artérielle peut raisonnablement être évitée ou remplacée par une technique alternative. Des exemples concrets y sont abordés, ainsi que des exercices pratiques, un projet de procédure écrite et le rappel de notions fondamentales en physiologie respiratoire appliquée. Pour citer cette revue : Ann. Fr. Med. Urgence 1 (2011). Mots clés Gazométrie artérielle · Gazométrie veineuse · Saturométrie · UrgencesAbstract Arterial blood gas measurement is a daily diagnostic tool for the emergency physician. These values are also used for evaluating the prognosis of certain conditions and making therapeutic decisions. ABG sampling is however a painful and invasive act, exposing both the patient and the healthworker to a real, though minimal, risk of complication. In the last couple of years, authors have been investigating alternative techniques to replace ABG sampling: venous blood gas sampling and saturometry by pulse oxymetry. This article aims to revise the indications of arterial blood gas analysis, and to study the circumstances in which arterial blood sampling can be avoided, and replaced by an alternative technique. Concrete examples will be analysed, practical exercises given, a written procedure proposed, and fundamental principles of applied respiratory physiology reviewed. To cite this journal: Ann. Fr. Med. Urgence 1 (2011).Une patiente de 70 ans, aux antécédents de bronchite chronique et de dépression, est admise somnolente et dyspnéique par les ambulanciers. Si ses paramètres hémodynamiques sont satisfaisants, sa saturation pulsée (SpO 2 ) n'est que de 77 %. Vous souhaitez connaître la situation ventilatoire de la patiente, car vous craignez une hypercapnie expliquant sa somnolence. Le gaz sanguin veineux réalisé dès l'arrivée objective un pH à 7,31 et une pression veineuse en CO 2 (PvCO 2 ) à 68 mmHg.Une jeune patiente de 18 ans est impliquée dans l'incendie de sa maison. Sa SpO 2 initiale est de 97 %. Face à ses plaintes de céphalées, vous souhaitez évaluer ses taux de monoxyde de carbone HbCO et de lactate. Pour éviter la douleur d'un prélèvement artériel radial, vous vous contentez d'un gaz sanguin veineux qui montre un HbCO à 20 % et un lactate à 0,8 Meq/l. Un patient de 23 ans diabétique insulinodépendant est admis somnolent et présente une respiration de type Kussmaul. Sa glycémie au doigt e...

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“…The first of these has been the focus of a PhD project [69,70,71]. Since the results of these stages are similar only the latter will be discussed in this dissertation.…”

Section: Evaluation With Studies Designed Specifically To Test Relevamentioning

confidence: 99%

“…In considering the role of ARTY it is important however, to ask the question as to whether ARTY is necessary or whether peripheral venous or indeed capillary blood could not be used to assess the patient's acid-base status without the use of ARTY [110,111]. For pH and PCO 2 it has been shown that the use of ARTY halves the standard deviation of the precision in which arterial values can be estimated [70,71], and for calculation of PO 2 no reasonable values can be obtained without ARTY [70]. These improvements are obtained cheaply, with the only overhead being the measurement of pulse It has been argued that ARTY conversions of peripheral venous blood are no better than direct measurement of capillary samples [110].…”

mentioning

confidence: 99%

Correlation between acid–base parameters measured in arterial blood and venous blood sampled peripherally, from vena cavae superior, and from the pulmonary artery

Cited by 44 publications

References 13 publications

Converting venous acid-base and oxygen status to arterial in patients with lung disease

Converting venous acid-base and oxygen status to arterial in patients with lung disease

Faut-il encore réaliser des gazométries artérielles au service des urgences ?

The Intelligent Ventilator (INVENT) project: The role of mathematical models in translating physiological knowledge into clinical practice

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