Correlation between a Cutometer<sup>®</sup> and quantitative evaluation using Moire topography in age‐related skin elasticity

Background: Skin reaction to spaceflight has not really been studied yet, although the skin has a very important barrier function to protect the body and can contribute to a more general understanding of physiology. It is proposed here to make a more thorough investigation of the skin during long-term spaceflight, using noninvasive techniques. Aims: The aim of the present Skin-B study is to investigate the kinetics and range of possible skin modifications during long-duration spaceflights and their recovery. Methods: In order to investigate the effect on skin physiological parameters during spaceflight, measurements were carried out on 6 astronauts with respect to skin hydration, transepidermal water loss/barrier function, and surface evaluation of the living skin in orbit. Additional measured parameters on the ground were skin elasticity, skin density and thickness, as well as microcirculation. Results: Data from the Skin-B subjects (n = 6) contradict the results obtained in the previous pilot study SkinCare (n = 1 subject). In the present study, no deterioration of the skin was found but rather an improvement in skin hydration and skin barrier function, and no changes or improvement in the appearance of the skin surface. Furthermore, the skin density and skin thickness as well as skin elasticity values were unchanged from pre-flight values. Conclusion: In conclusion, we found that spaceflight under present conditions has no negative impact on skin physiological parameters.

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“…R7 is used as the main parameter for assessing skin elasticity and aging [5]. Here, the higher the value, the more elastic the skin.…”

Section: Resultsmentioning

confidence: 99%

Current Data on Effects of Long-Term Missions on the International Space Station on Skin Physiological Parameters

Braun

Binder

Grosch

et al. 2018

Skin Pharmacol Physiol

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“…In addition, at the beginning and again after 12 weeks, a 4-mm punch biopsy was obtained from buttock skin for analysis of molecular markers. elastic is the skin [19] . As shown in figure 3 , both parameters significantly (p !…”

Section: Resultsmentioning

confidence: 99%

Pycnogenol® Effects on Skin Elasticity and Hydration Coincide with Increased Gene Expressions of Collagen Type I and Hyaluronic Acid Synthase in Women

Marini¹,

Grether‐Beck²,

Jaenicke³

et al. 2012

Skin Pharmacol Physiol

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Introduction and Objectives: In recent years there has been an increasing interest in the use of nutritional supplements to benefit human skin. Molecular evidence substantiating such effects, however, is scarce. In the present study we investigated whether nutritional supplementation of women with the standardized pine bark extract Pycnogenol® will improve their cosmetic appearance and relate these effects to expression of corresponding molecular markers of their skin. Materials and Methods: For this purpose 20 healthy postmenopausal women were supplemented with Pycnogenol for 12 weeks. Before, during and after supplementation, their skin condition was assessed (i) by employing non-invasive, biophysical methods including corneometry, cutometry, visioscan and ultrasound analyses and (ii) by taking biopsies and subsequent PCR for gene expression analyses related to extracellular matrix homeostasis. Results: Pycnogenol supplementation was well tolerated in all volunteers. Pycnogenol significantly improved hydration and elasticity of skin. These effects were most pronounced in women presenting with dry skin conditions prior to the start of supplementation. The skin-physiological improvement was accompanied by a significant increase in the mRNA expression of hyaluronic acid synthase-1 (HAS-1), an enzyme critically involved in the synthesis of hyaluronic acid, and a noticeable increase in gene expression involved in collagen de novo synthesis. Conclusions: This study provides skin-physiological and for the first time molecular evidence that Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity. These effects are most likely due to an increased synthesis of extracellular matrix molecules such as hyaluronic acid and possibly collagen. Pycnogenol supplementation may thus be useful to counteract the clinical signs of skin aging.

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“…For this purpose, new criteria of breast sagging was established using the real breast images of Korean women (Figure 2). Although Moiré topography has been widely used to evaluate facial skin sagging [11] and photographic grading criteria for facial skin sagging has been previously established by evaluating cheeks [12], no criteria for breast sagging has been reported previously. Thus this is the first study that has employed Moiré topography to evaluate breast sagging.…”

Section: Correlation Between the Parameters Of The Breastmentioning

confidence: 99%

Assessment of the Breast-Firmming Effects of a Cosmetic Preparation with Moiré Tophography in Combination with 2D and 3D Digital Image Analyses

서영경¹,

유미애²,

류자현³

et al. 2012

Journal of the Society of Cosmetic Scientists of Korea

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Cosmetic products which might augment the breast have attracted an attention and objective methods for the evaluation of such products are in high demand. This study was conducted to establish a method for assessing the breast-firmming effects of cosmetics. This study included a total of 30 healthy Korean females aged 20-50 years. A cosmetic product was applied by massaging it onto the breast twice a day for 8 weeks. Measurement of breast girth with a tape ruler, 2D and 3D digital image analyses, and Moiré topographic analysis were performed before and following the treatment. The application of a cosmetic onto the breast significantly increased breast girth at 2, 4 and 8 weeks without a significant change in underbreast girth, implicating the breast might be augmented. The 2D image analysis indicated that the arc length of the breast which represents the surface distance from the nipple to 1) † 주 저자 (e-mail: dermapro@dermapro.co.kr)the periphery of the under-breast was significantly increased at 2, 4 and 8 weeks. The height of the breast which represents the perpendicular distance from the nipple to the periphery of the under-breast was also increased significantly at 4 and 8 weeks. The 3D image analysis of body surface also demonstrated a significant increase of breast volume at 2, 4 and 8 weeks. Moiré topographic analysis indicated that breast sagging was significantly reduced at 2, 4 and 8 weeks. The results of this study suggest that Moiré topography in combination with 2D and 3D digital image analyses may be useful for evaluating the breast-augmenting effects of cosmetics.

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Correlation between a Cutometer^® and quantitative evaluation using Moire topography in age‐related skin elasticity

Abstract: It is considered that Cutometer parameters R7 and R2 are used as main parameters to assess skin elasticity and aging. And our studies using Moire topography on the face have confirmed that instrumental measurements reflect the decrease in skin elasticity, which is perceived visually.

Cited by 99 publications

References 7 publications

Current Data on Effects of Long-Term Missions on the International Space Station on Skin Physiological Parameters

Current Data on Effects of Long-Term Missions on the International Space Station on Skin Physiological Parameters

Pycnogenol® Effects on Skin Elasticity and Hydration Coincide with Increased Gene Expressions of Collagen Type I and Hyaluronic Acid Synthase in Women

Assessment of the Breast-Firmming Effects of a Cosmetic Preparation with Moiré Tophography in Combination with 2D and 3D Digital Image Analyses

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Correlation between a Cutometer® and quantitative evaluation using Moire topography in age‐related skin elasticity

Abstract: It is considered that Cutometer parameters R7 and R2 are used as main parameters to assess skin elasticity and aging. And our studies using Moire topography on the face have confirmed that instrumental measurements reflect the decrease in skin elasticity, which is perceived visually.

Cited by 99 publications

References 7 publications

Current Data on Effects of Long-Term Missions on the International Space Station on Skin Physiological Parameters

Current Data on Effects of Long-Term Missions on the International Space Station on Skin Physiological Parameters

Pycnogenol® Effects on Skin Elasticity and Hydration Coincide with Increased Gene Expressions of Collagen Type I and Hyaluronic Acid Synthase in Women

Assessment of the Breast-Firmming Effects of a Cosmetic Preparation with Moiré Tophography in Combination with 2D and 3D Digital Image Analyses

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Correlation between a Cutometer^® and quantitative evaluation using Moire topography in age‐related skin elasticity