Correlating diameter, mechanical and structural properties of poly(l-lactide) fibres from needleless electrospinning

Electrospun biodegradable poly(ε‐caprolactone) membranes for annulus fibrosus repair: Long‐term material stability and mechanical competence

“…A direct linear relationship between modulus and crystalline fraction has been observed experimentally in ES single fibers of similar semicrystalline polymers 56 as well as theoretically 57 . The membranes made up of medium diameter fibers showed an anomalous measurement at time point 180 days that was inconsistent with possible material behavior as well as with observations found in literature and membranes with fibers of other diameters.…”

“…This finding implies surface area controlled process, as when the easily accessible surface region is degraded, the bond cleavage that relies on hydration, proceeds at much slower pace in the bulk. Hence, thick fibers reached the plateau degradation state much quicker than thin fibers that have much more surface relative to bulk.A direct linear relationship between modulus and crystalline fraction has been observed experimentally in ES single fibers of similar semicrystalline polymers56 as well as theoretically 57. The membranes made up of medium diameter fibers showed an anomalous measurement at time point 180 days that was inconsistent with possible material behavior as well as with observations found in literature and membranes with fibers of other diameters.…”

“…58 The mismatch between the expected change in material properties and observations on ES networks arise from the complex fiber-fiber interactions which play a key role during fiber reorientation under stress. 56,59 In particular, inter-fiber adhesion, which plays one of the key roles, 60 ± 13.1 SD. 71 Others recorded even lower strains at failure of 13% to 25%.…”

Structural insights into semicrystalline states of electrospun nanofibers: a multiscale analytical approach

“…[16][17][18] The combined role of polymer chemical structure and nanofiber alignment shows a significant effect in promoting interactions with cells, such as controlling the phenotype and morphology of osteoblasts 16 and skeletal myoblasts. 14,15,19 In vascular graft applications, topography driven from the size distribution of nanofibers influences the platelets adhesion on membranes and the blood compatibility. 20 It is well understood that the folding of the polymeric chains into nanofibers and their morphology is highly dependent not only on the conductivity of the electrospinning solution, the spinning parameters, 21 and the post-treatment of the nanofiber membranes, 22 but also on the polymer type and environmental conditions.…”

On the Nanoscale Mapping of the Mechanical and Piezoelectric Properties of Poly (L-Lactic Acid) Electrospun Nanofibers

“…This size effect on the elastic modulus of nanofibers has been reported in numerous studies. It has been proved that orientation in crystalline and amorphous domains are higher in thinner fibers, resulting in an increase of elastic modulus [51][52][53]. Since tapping mode AFM measurements showed that there is a reduction of about 30% in diameter of nanofibers from the annealing process (from 210 ± 88 nm for the pristine fibers to 160 ± 44 nm for the annealed samples), for a meaningful comparison, we should compare the elastic modulus of annealed nanofibers to that of as-spun nanofibers with a relatively higher diameter.…”