Correlates of Hip Cartilage Defects: A Cross-sectional Study in Older Adults

Abstract

Grade 2 defects in both sexes and grade 1 defects (mostly in men) are associated with clinical, demographic, and structural factors relevant for OA. Damage to the hip cartilage could be one of the major causes of rapid disease progression and pathophysiology of hip defects. The topic needs further study.

Hip Shape as a Predictor of Osteoarthritis Progression in a Prospective Population Cohort

“…Although OA is a disease of the whole joint, bone and cartilage remain the focus of its clinical manifestation . Structural changes such as bone marrow lesions (BMLs) and cartilage defects are linked with the progression of hip OA . In addition to these, the morphology of the hip can predict the development of hip OA , but most current assessments are semiquantitative and focus on changes in the cartilage and the presence of bony outgrowths .…”

The association between ambulatory activity, body composition and hip or knee joint replacement due to osteoarthritis: a prospective cohort study

“…This is consistent with previous studies reporting that self-reported AA significantly reduced the risk of HR 8 and that leisure-time PA was protective against HR in women 23 . In addition, a recent cross-sectional study using our same cohort showed that higher levels of AA was associated with a lower prevalence of hip cartilage damage measured by MRI 31 . In contrast, a few earlier reports suggested that PA was associated with an increased risk of HR 22,32,33 or no association with HR 9,34 .…”

Predictors of total hip replacement in community based older adults: a cohort study

“…BMLs, cartilage defects) have been previously demonstrated in patients with hip OA. (15,16) Similarly, particular hip shapes correlated to MRI features of hip OA. (8) In this cohort, BMLs were signi cantly associated with a higher risk of THR.…”

“…(5-8) Particular patterns of hip shape such as reduced acetabular coverage (8), non-spherical femoral heads (8) and cam impingement (abnormally shaped head of femur leading to abnormal contact between femoral head and acetabulum)(9) predict progression of hip OA and risk of THR. (8)(9)(10)(11) Hip bone marrow lesions (BMLs), hip cartilage defects (12)(13)(14)(15)(16) and higher BMD of the proximal femur (17) are independent risk factors for progression of hip OA. Greater BMD also increases risk of THR (18,19); hip BMLs and cartilage defects may do likewise but these associations have not been studied.…”