Correlates and outcomes of preserved left ventricular systolic function among older adults hospitalized with heart failure

Higher New York Heart Association classes and increased mortality and hospitalization in patients with heart failure and preserved left ventricular function

“…These findings are important as NYHA class is a useful prognostic tool in patients with heart failure and preserved systolic function is especially common among community dwelling elderly heart failure patients. [13][14][15][16][17] We also noted that age, diabetes, chronic kidney disease, use of non-potassium-sparing diuretics, and increased cardiothoracic ratio were associated with poor prognosis, as has been found in patients with systolic heart failure. As observed in the DIG ancillary study, use of digoxin was not associated with mortality or all cause hospitalization.…”

Outcomes in ambulatory chronic systolic and diastolic heart failure: A propensity score analysis

“…1, 2, 4, 6, 7 Many of these studies included HF patients with valvular heart disease and arrhythmias (especially atrial fibrillation). 4,[8][9][10] On the other hand, community-based studies of outcomes in DHF suffer from small sample sizes. 1, 2, 7…”

Preditores clínicos de fração de ejeção preservada em insuficiência cardíaca descompensada

“…Among patients hospitalized due to acute decompensated HF, data on clinical course and outcomes of patients with preserved LVEF is limited. Previous reports demonstrated conflicting findings about the clinical impact on long-term outcomes, and scarce data are available on in-hospital event rates 10,11 . A Canadian cohort of hospitalized HF patients did not observe significant differences for both in-hospital and 1-year mortality rates between patients with systolic dysfunction and those with preserved ejection fraction (4.9% and 3.8%, respectively, for in-hospital death) 26 .…”

“…Several studies tried to identify clinical variables that could be associated with preserved LVEF, and therefore help in its identification before imaging assessment of systolic and diastolic parameters 11,[19][20][21]27 . Some of these characteristics have been systematically reported in cohorts of hospitalized HF patients, such as older age, female gender and lower prevalence of previous history of myocardial infarction or coronary artery disease among subjects with preserved LVEF 11,20,21,29 .…”

“…Prevalence of preserved LVEF in HF cohorts, however, may vary greatly, depending on diagnostic criteria, study setting and design. It is estimated that approximately 30-50% of hospital admissions attributed to decompensated HF occur in patients without systolic dysfunction [9][10][11][12] . Furthermore, hospitalizations for HF with preserved LVEF have become increasingly more frequent in the last two decades 13 .…”