Correlação entre os resultados laboratoriais e os sinais e sintomas clínicos das pacientes com candidíase vulvovaginal e relevância dos parceiros sexuais na manutenção da infecção em São Paulo, Brasil

Abstract

Correlação entre os resultados laboratoriais e os sinais e sintomas clínicos das pacientes com candidíase vulvovaginal e relevância dos parceiros sexuais na manutenção da infecção em São Paulo, Brasil Abstract PURPOSE: to relate yeasts identifi ed by laboratory tests to clinical signs and symptoms in patients with vulvovaginal candidiasis, and to investigate the importance of the sexual partners in the recurrence of the infection. METHODS: from July 2001 to July 2003, a sample of 179 patients aged from 18 to 65 years old, with clinical suspicion of fungal vaginitis were analyzed in a prospective study in Great São Paulo. Exclusion criteria included: pregnancy, impaired intrinsic or extrinsic immune response (including Aids), diabetes or immunosuppression; patients undergoing corticosteroid, antibiotic or hormone therapy, in post menopause, with intrauterine device (IUD) or making use of vaginal douches or spemicides. Samples of vaginal and penis secretions from partners of patients with relapse of vaginitis episodes were collected for microscopy and fungal culture. Fungal colonies isolated in CHROMagar Candida were identifi ed by classical methods. Fisher's exact t-test was used to correlate the clinical picture with the yeasts isolated from patients. RESULTS: the most relevant clinical signs and symptoms were pruritus and vaginal discharge followed by erythema and edema, statistically independent from the etiological agent. Direct microscopy revealed yeasts in 77 patients with vulvovaginitis, and 40 Candida spp cultures were obtained. Candida albicans (70%), C. glabrata (20%), C. tropicalis (7,5%) and C. guilliermondii (2,5%) were identifi ed. The yeasts prevalent in partners were C. albicans and C. glabrata. The same species were detected in

Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors

“…Moreover, several studies have found that VVC occurs more frequently in the third decade of life and have suggested that this may be due to an increased sexual activity in this age group (Ahmad & Khan, 2009;Ako-Nai et al, 1993;Okungbowa et al, 2003). VVC is not considered a sexually-transmitted disease because it occurs in non-sexually active women and women can be vaginal colonized by Candida, but nevertheless, some studies have confirmed Candida sexual transmission (Boatto et al, 2007;Schmid et al, 1993). Thus, high frequency of sexual intercourse may lead to an increase of vaginal Candida load, possibly contributing to VVC episodes.…”

Identification and characteristics of Candida spp . in vaginal secretion of pregnant and non-pregnant patients

“…Además, generalmente en estudios de factores de virulencia y pruebas de sensibilidad a antifúngicos a partir de muestras clínicas, se parte de varias colonias de una placa de agar Sabouraud, el medio más utilizado para aislamiento de levaduras, donde no se diferencian morfologías que están relacionadas a especies. Consideramos fundamental el uso de agar cromogénico para detectar colonias mixtas que tendrían relación con las recidivas en vulvovaginitis por Candida (11,26,27 El diagnóstico de laboratorio en candidiasis vaginal es esencial para el tratamiento de la enfermedad ya que este se basa en el número y tipo de Candida. Los resultados obtenidos en este trabajo apuntan a la necesidad de continuar los estudios de vigilancia de las especies implicadas en la vaginitis por Candida y a un conocimiento más profundo de la epidemiología de las infecciones vaginales causadas por hongos.…”

Perfil do conhecimento de mulheres quanto aos fatores predisponentes ao desenvolvimento da candidíase vulvovaginal

“…Das que manifestaram sintomas, foi relatado o corrimento em grumos seguido da dispaurenia. Boatto et al (2007) em seu estudo aborda que os sinais e sintomas clínicos mais relevantes na CVV foram prurido e corrimento, seguidos por eritema e edema. Os achados de Gondo et al (2010) apontam elevada prevalência das alterações de flora vaginal, com pouca associação à sintomatologia, mas associação com achados do exame ginecológico.…”