Corrective Saccades in Unilateral and Bilateral Vestibular Hypofunction During Slow Rotation Expressed by Visually Enhanced VOR and VOR Suppression: Role of the Cerebellum

The Clinical Use of the Suppression Head Impulse Paradigm in Patients with Vestibulopathy: A Systematic Review

“…For vHIT, different tools were used. Nine studies [ 4 , 7 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ] used an Otometrics ICS impulse, one study [ 19 ] used an EyeSeeCamTM System, and one study [ 3 ] used a FireflyMV, Point Grey Research Inc. All instruments were validated with the gold standard scleral search coils. Three studies [ 4 , 7 , 12 ] evaluated patients within the first 3 days after the acute vestibular syndrome, and five studies evaluated patients in the sub-acute and chronic phases [ 13 , 15 , 17 , 18 , 19 ].…”

“…Nine studies [ 4 , 7 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ] used an Otometrics ICS impulse, one study [ 19 ] used an EyeSeeCamTM System, and one study [ 3 ] used a FireflyMV, Point Grey Research Inc. All instruments were validated with the gold standard scleral search coils. Three studies [ 4 , 7 , 12 ] evaluated patients within the first 3 days after the acute vestibular syndrome, and five studies evaluated patients in the sub-acute and chronic phases [ 13 , 15 , 17 , 18 , 19 ]. Two articles did not report the timing of the evaluation [ 16 , 20 ], and one study reported that the evaluation was performed in the acute phase without specifying the days since the onset [ 12 ].…”

“…In total, 9 out of 11 studies included patients with UV. In particular, five studies enrolled 86 patients with UV after vestibular neuritis (VN) [ 4 , 7 , 14 , 15 , 19 ], two studies enrolled 20 patients with UV after Menière’s disease [ 18 , 19 ], two studies included 43 patients with UV after treatment of vestibular schwannoma [ 3 , 18 ], and two studies enrolled UV patients without specifying the diagnosis [ 12 , 17 ]. In addition, 6 out of 11 studies enrolled patients with BV.…”

“…In addition, 6 out of 11 studies enrolled patients with BV. In particular, one study included a Lyme Disease patient with BV [ 13 ], five studies enrolled 16 patients with idiopathic BV [ 3 , 15 , 16 , 18 , 19 ], one study included 1 patient with genetic BV [ 16 ], and two studies enrolled 5 patients with BV after systemic gentamicin treatment [ 3 , 16 ]. Eight studies were observational [ 4 , 7 , 12 , 13 , 14 , 15 , 17 , 19 ], one study was a case-control study [ 3 ], and two studies were a non-randomized clinical trials [ 16 , 18 ].…”

“…Three out of eleven studies were carried out in Italy [ 4 , 12 , 13 ], two studies were carried out in Korea [ 7 , 14 ], and two studies were carried out in France [ 16 , 18 ]. The remaining four studies were performed in Turkey [ 19 ], Brazil [ 15 ], Spain [ 17 ], and jointly in Italy and Australia [ 3 ]. Two studies [ 12 , 19 ] were carried out in a University hospital, three studies were carried out in a tertiary referral hospital [ 4 , 14 , 16 ], one study was carried out in the emergency department [ 6 ], and five studies did not report information about the setting [ 3 , 13 , 15 , 17 , 18 ].…”