Correction to: The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink

Abstract

The above article originally published with an error present in the 2nd sentence in the 4th paragraph of the Discussion section. Originally reading B…Ours is the first study to report the effect of socio-economic status on the incidence of systemic sclerosis; we observed no effect of socio-economic status, as estimated by area-based deprivation data which is used as a proxy for socio-economic status and social class.^, this should instead have read B…A study in Southern Australia previously found no effect of socio-economic status on the incidence of systemic sclerosis [16]. We also observed no effect of socio-economic status, as estimated by area-based deprivation data which is used as a proxy for socio-economic status and social class.T he remainder of the article remains unchanged.The online version of the original article can be found at https://doi

Immunopathogenesis of Juvenile Systemic Sclerosis

“…Juvenile systemic sclerosis (jSSc) is a multisystem connective tissue disease characterized by skin induration and widespread fibrosis of internal organs. The incidence has been reported at 0.27–0.50 per million children per year in the UK and Finland (1, 2), with a prevalence of 3 per million (3–5). Less than 5% of SSc has an onset in childhood (6–8).…”

“…As compared with adults, children with jSSc have overall better outcomes, related to a lower frequency of major visceral organ involvement and lower mortality (6, 13, 17). During follow-up, interstitial lung involvement, gastroesophageal dysmotility, and renal involvement are significantly more common in adults, while arthritis and muscle inflammation are more common in children, because of the higher prevalence of the overlap form of jSSc (3, 4, 6).…”