Correction to: SARS-COV-2 infection in children and newborns: a systematic review

Liguoro, Ilaria; Pozzi, Chiara; Bonanni, Margherita; Ferrari, Maria Elena; Pusiol, Anna; Nocerino, Agostino; Vidal, Enrico; Cogo, Paola

doi:10.1007/s00431-021-03961-z

Cited by 8 publications

(8 citation statements)

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“…The reported fatality rate was 0.08% (6 patients). 24 Similarly low (0.28%) is the mortality rate reported by Wang et al 41 in a meta-analysis that collects data from more than 11,000 COVID-19 positive children. However, some pediatric patients may require hospitalization, particularly those with one or more comorbidities.…”

Section: Sars-cov-2 Infection and Covid-19 In Children Andmentioning

confidence: 85%

“…The most frequent are fever (46%), cough (37%), headache (15%), diarrhea (14%), sore throat (13%), nausea/vomiting (10%), myalgia (10%), abdominal pain (7%), rhinorrhea (7%) and shortness of breath (7%). 22,23 Several organ-specific involvements have been reported: heart failure, myocarditis, pericarditis, arrhythmias, pulmonary embolism in the cardiovascular system; [24][25][26] encephalopathy, stroke, Guillain-Barrè syndrome, cerebral edema, status epilepticus, transient ischemic attack in the nervous system; 27,28 urticarial, maculopapular, vesicular skin rash, livedo reticularis, chilblain-like lesions as skin manifestations. 29 The most fearful complication of COVID-19 infection in pediatric age is the multisystem inflammatory syndrome in children (MIS-C), described as early as April 2020.…”

Section: Sars-cov-2 Infection and Covid-19 In Children Andmentioning

confidence: 99%

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Covid-19 in Children and Adolescent: Characteristics and Specificities in Immunocompetent and Oncohematological Patients

Mercolini¹,

Cesaro²

2022

Mediterr J Hematol Infect Dis

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SARS-CoV-2 pandemic affected less children and adolescents, morbidity and mortality figures being inferior to that reported for adults. In this review we focused on the clinical course, risk factors for severe COVID-19, mortality, treatment options and prevention measures in the pediatric and adolescent setting with special attention to the pediatric oncohematological patients. In this subgroups of patients, SARS-CoV-2 infection was often asyntomatic but 47 to 68% of patients require hospitalization and 9-10% of those hospitalized needed intensive care with a COVID-19 attributable mortality of about 4%. The multisystem inflammatory syndrome associated to Coronavirus 2019 was less frequent than that reported in the non-oncohematological pediatric population. Noteworthy, the course of COVID-19 was more severe in low-middle income countries. The key measures to prevent SARS-CoV-2 infection are the reduction of patients exposure to the SARS-CoV-2 and vaccination, now available fore care givers and parents and for patients and siblings > 12 years old. The treatment of COVID-19 in pediatric patients was mainly based on supportive care with dexamethasone and heparin prophylaxis for severely ill patients. Other measures, such as convalescent plasma, remdesivir and monoclonal antibodies have been used in limited case or within experimental protocols. Further studies are needed on the risk factors and outcome of SARS-CoV-2 infection in the pediatric immunocompromised patients.

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Section: Sars-cov-2 Infection and Covid-19 In Children Andmentioning

confidence: 85%

Section: Sars-cov-2 Infection and Covid-19 In Children Andmentioning

confidence: 99%

Covid-19 in Children and Adolescent: Characteristics and Specificities in Immunocompetent and Oncohematological Patients

Mercolini¹,

Cesaro²

2022

Mediterr J Hematol Infect Dis

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“…MANZOOR HUSSAIN 1 , MOHAMMAD ABDULLAH AL MAMUN 2 (shown in Table-I). Regarding clinical characteristics, majority of the children were admitted with fever (94.92%) & cough (79.69%).…”

Section: Impact Of Covid-19 On Child Life and Health In Bangladeshmentioning

confidence: 99%

“…1 Although severe instances of COVID-19 in children, including fatal cases have been reported, most children appear to have asymptomatic, mild or moderate disease and recover within one to two weeks of disease onset. 2 The present context in Bangladesh indicates a rise in paediatric patients including some casualties. 3,4 The age-distribution data on confirmed cases COVID-19 in Bangladesh also indicates that the present local situation in Bangladesh seems to be different in comparison to the earlier scenario.…”

Section: Introductionmentioning

confidence: 98%

Impact of COVID-19 on Child Life & Health in Bangladesh

Hussain

Mamun

2021

Bangladesh J Child Health

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“…Therefore, rectal swabs analysis at birth should always be performed. In addition, Liguoro et al argue that newborns are often tested for SARS-CoV-2 only if symptomatic ( Liguoro et al, 2021 ); this might reduce the possibility of detecting a vertical transmission. Indeed, the evidence on the tissue tropism of SARS-CoV-2 suggests the potential infection of other organs and tissues rather than the respiratory tract in infants, although the clinical outcomes are still unconfirmed.…”

Section: Discussionmentioning

confidence: 99%

What is the Hidden Biological Mechanism Underlying the Possible SARS-CoV-2 Vertical Transmission? A Mini Review

et al. 2022

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2) represents an emerging infection that is spreading around the world. Among susceptible patients, pregnant women are more likely to develop serious complications and negative obstetric outcomes. Vertical transmission constitutes a debating issue which has not been completely understood. This review aims at describing the currently available evidence on SARS-CoV2 vertical transmission. We carried out a computerized literature search in the Cochrane Library, PubMed, Scopus and Web of Science, selecting the most relevant studies on vertical transmission from the outbreak onset until February 2022. The analysis of the available literature identifies the presence of SARS-CoV2 genome in different biological specimens, confirming the hypothesis that a transplacental infection can occur. In spite of the high number of infected people around the world, mother-to-child infections have been infrequently reported but it can be observed under certain biologic conditions. A deep knowledge of the underlying mechanisms of SARS-CoV2 vertical transmission is of paramount importance for planning an adequate management for the affected mothers and newborns.

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Correction to: SARS-COV-2 infection in children and newborns: a systematic review

Cited by 8 publications

References 0 publications

Covid-19 in Children and Adolescent: Characteristics and Specificities in Immunocompetent and Oncohematological Patients

Covid-19 in Children and Adolescent: Characteristics and Specificities in Immunocompetent and Oncohematological Patients

Impact of COVID-19 on Child Life & Health in Bangladesh

What is the Hidden Biological Mechanism Underlying the Possible SARS-CoV-2 Vertical Transmission? A Mini Review

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