Correction to: Peritoneal dialysis-related peritonitis caused by Gordonia bronchialis: first pediatric report

Bruno, Valentina; Tjon, James; Lin, Sandy; Kazmi, Kescha; Zappitelli, Michael; Harvey, Elizabeth

doi:10.1007/s00467-021-05360-w

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“…Our search identified 57 eligible articles, of which 92 documented human infections associated with Gordonia spp. were reported [1–5, 7–58] (see for details).…”

Section: Discussionmentioning

confidence: 99%

Gordonia sputi-associated bloodstream infection in a renal transplant patient with chronic indwelling central venous catheter: a case report and literature review

Broderick

Stefanovic

et al. 2023

Access Microbiology

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Introduction. Although rare, human infections caused by Gordonia spp. have been reported, especially within the immunocompromised population and those with long-term indwelling devices. We report a case of Gordonia spp. bacteraemia in a renal transplant patient and present a literature review on microbiological identification methods of this organism. Case Presentation. A 62-year-old female renal transplant recipient admitted to hospital with a 2-month history of dry cough and fevers occurring weekly when receiving electrolyte replacement infusions via a Groshong line. Over 2 weeks, blood cultures repeatedly isolated a Gram-positive bacillus solely in aerobic bottles, and this was initially reported as Rhodococcus spp. by the local microbiology laboratory. Chest computed tomography (CT) showed multiple ground-glass lung opacities suggestive of septic pulmonary emboli. As central line-associated bloodstream infection was suspected, empirical antibiotics were initiated and the Groshong line was removed. The Gram-positive bacillus was later confirmed by the reference laboratory as Gordonia sputi via 16S rRNA sequencing. Vancomycin and ciprofloxacin for a duration of 6 weeks were completed as targeted antimicrobial therapy. After treatment, the patient remained symptom-free with marked improvement on repeat CT chest imaging. Conclusion. This case illustrates the challenges surrounding identification of Gordonia spp. and other aerobic actinomycetes. 16S rRNA gene sequencing may be a preferred identification method, especially when initial workup of a weakly acid-fast organism fails to make an identification or shows discrepant results using traditional diagnostic modalities.

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“…Our search identified 57 eligible articles, of which 92 documented human infections associated with Gordonia spp. were reported [1–5, 7–58] (see for details).…”

Section: Discussionmentioning

confidence: 99%