Correction to: Outcome of Repeat Pulmonary Metastasectomy

Krüger, M.; Franzke, K.; Rajab, Taufiek Konrad; Nadler, Fabian; Möbius-Winkler, Moritz; Zinne, Norman; Schulz, Daniel; Möller, Miriam; Schütte, Wolfgang; Ermitsch, Michael; Redwan, Bassam; Schega, O; Biancosino, Christian

doi:10.1007/5584_2021_650

Cited by 1 publication

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“…To our knowledge, there has been little information on the mid- to long-term outcomes after third PM. Krüger et al [ 12 ] reported the outcomes of repeat PM from a multicentre trial. In their report, a total of 621 patients underwent first PM, and of these, 64 patients underwent a second PM, 35 underwent a third PM, 12 underwent a fourth PM and 6 underwent a fifth PM.…”

Section: Discussionmentioning

confidence: 99%

“…In the report of The International Registry of Lung Metastases, which included 5206 cases of PM, 15% of patients underwent repeat PM, and only 5% underwent PM ≥3 times [ 11 ]. Krüger et al reported that 35 of 621 patients (6%) who underwent first PM subsequently underwent third PM [ 12 ]. Recently, Mills et al [ 13 ] reported the short-term outcomes of third PM, concluding that the third PM can be performed safely and feasibly in select patients.…”

Section: Introductionmentioning

confidence: 99%

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Outcomes and prognostic factors of repeat pulmonary metastasectomy

Kanzaki,

Watari,

Omura

et al. 2024

Interdisciplinary CardioVascular and Thoracic Surgery

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OBJECTIVES Information on prognostic factors after repeat pulmonary metastasectomy (PM) is limited, and outcomes after a third PM are not well documented. METHODS A single-institute retrospective study was conducted. Between 2000 and 2020, 68 patients underwent repeat PM for pulmonary metastases from various cancers. Outcomes and prognostic factors for the second PM and outcomes after the third PM were analyzed. RESULTS This study included 39 men and 29 women. The mean age at second PM was 53.2 years old. The primary tumors were soft tissue sarcoma in 24 patients, colorectal cancer in 19, and osteosarcoma in 10. The interval between the first PM procedure and detection of pulmonary metastasis after the first PM (months) was ≤12 in 37 patients and >12 in 31 patients. At the second PM, 20 patients underwent lobectomy or bilobectomy, and 48 underwent sublobar resection. Complete resection was achieved in 60 patients, and 52 patients experienced recurrence after the second PM. The 5-year relapse-free survival (RFS) and overall survival (OS) rates after the second PM were 27% and 48%, respectively. Multivariable analysis revealed that the interval between the first PM and the subsequent detection of pulmonary metastasis (≤12 months) was a poor prognostic factor for both RFS and OS after the second PM. Seventeen patients underwent a third PM, three of whom achieved a three-year disease-free survival. CONCLUSIONS Patients with a period of > 12 months between the first PM and the subsequent detection of pulmonary metastases showed favourable outcomes and are thus considered good candidates for second PM. A third PM may be beneficial for selected patients.

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Section: Discussionmentioning

confidence: 99%