Correction to: Normalization of magnesium deficiency attenuated mechanical allodynia, depressive-like behaviors, and memory deficits associated with cyclophosphamide-induced cystitis by inhibiting TNF-α/NF-κB signaling in female rats

MiR‐9‐enriched mesenchymal stem cells derived exosomes prevent cystitis‐induced bladder pain via suppressing TLR4/NLRP3 pathway in interstitial cystitis mice

“…Bladder pain is a prominent symptom of IC/BPS, characterized by hyperalgesia, abnormal pain and spontaneous pain, and can even cause mental dysfunction such as depression, anxiety, panic, etc., seriously affecting patients' daily work ability and quality of life 3–5 . However, at present, the treatment of IC/BPS bladder pain is difficult and ineffective, and there is no clear etiology and effective treatment 6 . To explore the molecular mechanism of bladder pain, pain‐sensitizing targets and treatment methods in IC/BPS is of great practical significance for improving the symptoms of patients with bladder pain and further preventing the accompanying psychiatric diseases.…”

“…[3][4][5] However, at present, the treatment of IC/ BPS bladder pain is difficult and ineffective, and there is no clear etiology and effective treatment. 6 To explore the molecular mechanism of bladder pain, pain-sensitizing targets and treatment methods in IC/BPS is of great practical significance for improving the symptoms of patients with bladder pain and further preventing the accompanying psychiatric diseases. Our previous studies have demonstrated that altered TLR4 activation plays a crucial role in bladder nociception independent of inflammation and urianry dysfunction in the IC/BPS model, providing clues for potential mechanisms and therapeutic targets of IC/BPS pain.…”