“…contribute less than 1% of the total ethanol production, although the production rate of global plant biomass was calculated at approximately 200 × 10 9 tons/year (Saini, Saini, & Tewari, 2015). This lack of cellulosic ethanol production at commercial scale can be attributed to multiple factors; recalcitrance of the biomass for deconstruction (Holwerda et al, 2019), inability of industrial strains of Saccharomyces cerevisiae to ferment pentose sugars derived from hemicellulose (Subtil & Boles, 2011), cost of enzymes needed for depolymerization of cellulose to glucose (Klein-Marcuschamer, Oleskowicz-Popiel, Simmons, & Blanch, 2012), and inhibitory compounds generated during pretreatment of biomass that affect the rate of fermentation (Altaner & Saake, 2016;Liu, Zhou, Wang, Wang, & Fan, 2016).…”