Correction to: Interleukin‑23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin‑17A

Behrends, Jochen; Erdmann, Hanna; Rousseau, Jasmin; Hölscher, Christoph; Volz, Johanna; Prinz, Immo; Lindenstrøm, Thomas

doi:10.1007/s00109-021-02142-7

J Mol Med

2021

DOI: 10.1007/s00109-021-02142-7

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Correction to: Interleukin‑23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin‑17A

Jochen Behrends

Hanna Erdmann

Jasmin Rousseau

et al.

Abstract: The citations and references do not match in the previously published paper.The original article has been corrected.

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Serum lymphocytes and cytokines: diagnostic value and influence on the immune status in patients with pulmonary tuberculosis

Ma1,

Li1,

Liu1

et al. 2023

J Bras Pneumol.

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Objective: To determine the absolute number of serum T lymphocytes and cytokine levels and the characteristics of patients with active pulmonary tuberculosis and to assess their effect on the immune status of these patients and their diagnostic and predictive value for tuberculosis. Methods: We included 1,069 patients with active tuberculosis, 51 patients with latent tuberculosis infection, and 600 health individuals. Absolute serum T-lymphocyte counts and cytokine levels were quantified. Results: T lymphocytes were significantly reduced in patients with active tuberculosis when compared with healthy individuals. The immune function of patients gradually decreased with age and was stronger in female patients than in males. Th1 cells expressed higher levels of cytokines than did Th2 cells. Logistic regression analysis showed that reduced CD3+ T, CD8+ T, and NK cell counts, as well as reduced IL-4 and IFN-? expression, were independent influencing factors for active tuberculosis. ROC analysis showed that the sensitivity and specificity of absolute CD3+ T and CD8+ T lymphocyte counts and combined factors were significantly higher than were those of IL-4 and IFN-? for diagnosing active tuberculosis. Conclusions: Serum T-lymphocyte counts and cytokine levels can assess the immune status of tuberculosis patients; they are also useful biomarkers for predicting and diagnosing tuberculosis.

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Serum lymphocytes and cytokines: diagnostic value and influence on the immune status in patients with pulmonary tuberculosis

Ma1,

Li1,

Liu1

et al. 2023

J Bras Pneumol.

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show abstract

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Correction to: Interleukin‑23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin‑17A

Abstract: The citations and references do not match in the previously published paper.The original article has been corrected.

Cited by 1 publication

References 0 publications

Serum lymphocytes and cytokines: diagnostic value and influence on the immune status in patients with pulmonary tuberculosis

Serum lymphocytes and cytokines: diagnostic value and influence on the immune status in patients with pulmonary tuberculosis

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