Correction to: In Vivo Evaluation of Mg–5%Zn–2%Nd Alloy as an Innovative Biodegradable Implant Material

Abstract

The article In Vivo Evaluation of Mg-5%Zn-2%Nd Alloy as an Innovative Biodegradable Implant Materialwritten by Elkaiam et al. was originally published electronically on the publisher's internet portal (currently SpringerLink) on September 17

In vitro and in vivo degradation behavior of Mg-0.45Zn-0.45Ca (ZX00) screws for orthopedic applications

“…These drawbacks of permanent implants could inhibit the bone formation or bone resorption processes and necessitate a second surgery to retrieve or remove them after the bone has healed [ 7 ]. On the other hand, due to its similar mechanical properties close to the bone, such as elastic modulus and density, Mg and its alloys are promising biodegradable materials [ 3 , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] ]. Furthermore, as a material for orthopedic applications, Mg-based devices have shown osteoinductive and osteoconductive effects, substantially high mineral apposition rates, and enhanced bone mass around Mg-implants [ 17 , 18 ].…”

“…Studies show that resistance to general and pitting corrosion of Mg alloys is improved by adding Ca [ 9 , 23 , 33 , 34 ]. Zn also enhances the corrosion resistance of Mg alloys via a solid hardening mechanism and may reduce hydrogen evolution during the degradation [ 8 , 28 , 29 , 34 , 35 ]. Moreover, Zn is essential for numerous biological functions in the human body, such as stimulation of new bone formation, preservation of bone mass, signal transmission, apoptosis regulation, and gene expression [ 36 ].…”