Correction to Distribution and Excretion of Bilberry Anthocyanins in Mice

Sakakibara, Hiroyuki; Ogawa, Takeshi; Koyanagi, Akiharu; Kobayashi, Saori; Goda, Toshinao; Kumazawa, Shigenori; Kobayashi, Hirokazu; Shimoi, Kayoko

doi:10.1021/jf903424k

Cited by 4 publications

(1 citation statement)

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“…In swine studies, M3G reached peak concentrations in brain tissue (4.43 pmol/g) after bilberry extract intake and malvidin glycosides dominated in various tissues of blueberryfed pigs [235][236][237]. Mice also showed malvidin predominance in plasma and tissues after bilberry anthocyanin consumption [238]. In humans, malvidin glycosides ranked among the top urinary anthocyanin metabolites during blueberry juice consumption, alongside other C6-C3-C6 forms [233].…”

Section: Factors Influencing Pharmacokinetics Of Acnsmentioning

confidence: 96%

Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability

Ijinu,

De Lellis,

Shanmugarama

et al. 2023

Nutrients

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Anthocyanins (ACNs) have attracted considerable attention for their potential to modulate the immune system. Research has revealed their antioxidant and anti-inflammatory properties, which play a crucial role in immune regulation by influencing key immune cells, such as lymphocytes, macrophages, and dendritic cells. Moreover, ACNs contribute towards maintaining a balance between proinflammatory and anti-inflammatory cytokines, thus promoting immune health. Beyond their direct effects on immune cells, ACNs significantly impact gut health and the microbiota, essential factors in immune regulation. Emerging evidence suggests that they positively influence the composition of the gut microbiome, enhancing their immunomodulatory effects. Furthermore, these compounds synergize with other bioactive substances, such as vitamins and minerals, further enhancing their potential as immune-supporting dietary supplements. However, detailed clinical studies must fully validate these findings and determine safe dosages across varied populations. Incorporating these natural compounds into functional foods or supplements could revolutionize the management of immune-related conditions. Personalized nutrition and healthcare strategies may be developed to enhance overall well-being and immune resilience by fully understanding the mechanisms underlying the actions of their components. Recent advancements in delivery methods have focused on improving the bioavailability and effectiveness of ACNs, providing promising avenues for future applications.

show abstract

Section: Factors Influencing Pharmacokinetics Of Acnsmentioning

confidence: 96%

Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability

Ijinu,

De Lellis,

Shanmugarama

et al. 2023

Nutrients

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Visualization of the distribution of anthocyanin species in mice eyeball by matrix‐assisted laser desorption/ionization mass spectrometry imaging

Yamada

Zaima

Yoshimura

et al. 2018

Rapid Comm Mass Spectrometry

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Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability

Ijinu,

Lellis,

Shanmugarama

et al. 2023

Preprint

View full text Add to dashboard Cite

Anthocyanins (ACNs) have attracted considerable attention for their potential to modulate the immune system. Research has revealed their antioxidant and anti-inflammatory properties, which play a crucial role in immune regulation by influencing key immune cells such as lymphocytes, macrophages, and dendritic cells. Moreover, ACNs contribute to maintaining a balance between proinflammatory and anti-inflammatory cytokines, thus promoting immune health. Beyond their direct effects on immune cells, ACNs significantly impact gut health and the microbiota, essential factors in immune regulation. Emerging evidence suggests that they positively influence the composition of the gut microbiome that enhance the immunomodulatory effects of ACNs. Furthermore, these compounds synergize with other bioactive substances, such as vitamins and minerals, further enhancing their potential as immune-supporting dietary supplements. However, detailed clinical studies must fully validate these findings and determine safe dosages for different populations. Incorporating these natural compounds into functional foods or supplements can revolutionize the management of immune-related conditions. Personalized nutrition and healthcare strategies can be developed to enhance overall well-being and immune resilience by fully understanding the mechanisms underlying their actions. Recent advancements in delivery methods have focused on improving the bioavailability and effectiveness of ACNs, providing promising avenues for future applications.

show abstract

Correction to Distribution and Excretion of Bilberry Anthocyanins in Mice

Abstract: The first sentence of the left-hand column of p 1753 should be "No characteristic compound for nitrofurazone metabolite is given under EU legislation, and recent development methods for nitrofuran analysis still utilize SEM as marker residue for nitrofurazone abuse."

Cited by 4 publications

References 0 publications

Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability

Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability

Visualization of the distribution of anthocyanin species in mice eyeball by matrix‐assisted laser desorption/ionization mass spectrometry imaging

Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability

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